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Brand: PANACUR ® C GRANULES

Company: MERCK ANIMAL HEALTH


FORMULATION: «GRANULES» for oral administration, usually mixed with food

ACTIVE INGREDIENT(S): FENBENDAZOLE 222 mg/g (= 22.2%)

CHEMICAL CLASS of the active ingredient(s): BENZIMIDAZOLE


INDICATIONS: DOGS and CATS*


PARASITES CONTROLLED* (spectrum of activity):

* In some countries not available for cats


RECOMMENDED DOSE*:

UK and other countries:

  • 100 mg fenbendazole / kg bw for adult dogs and cats
  • 50 mg fenbendazole / kg for weaned puppies and kittens under 6 months pof age
  • 25 mg fenbendazole / kg for pregnant dogs
  • Frequency of treatment depending on the indication

USA and other countries

  • 50 mg fenbendazole / kg bw
  • Frequency of treatment depending on the indication

* Can be slightly different in some countries: read the product label!


SAFETY

  • LD50 (acute oral) in rats: n.a. for the granules. >10000 mg/kg for fenbendazole a.i.
  • Estimated Hazard Class according to the WHO: not applicable for veterinary medicines

Suspected poisoning? Read the articles on fenbendazole safety in this site.

You may be interested in the following articles in this site dealing with the general safety of veterinary products:


RESISTANCE PREVENTION

Risk of resistance development? LOW

There are no reports on resistance of dog or cat worms to benzimidazoles about 40 years after their introduction.

Learn more about resistance and how it develops.


MARKETING

Are the active ingredients of this product ORIGINAL* or GENERICS**?

  • Fenbendazole: GENERIC (introduced in the 1970s)

*Meaning that they are still patent protected and generics are not yet available
**Meaning that they have lost patent protection and may be acquired from manufacturers of generic active ingredients other than the holder of the original patent.

COUNTRIES where this product is marketed: USA, EU, and numerous other countries, perhaps with slightly different composition.
GENERIC BRANDS available? YES, in most countries.

Click here to learn more about GENERIC vs. ORIGINAL drugs.


COMMENTS

PANACUR is the original brand of a whole series of fenbendazole products introduced by HOECHST in the 1970s for livestock, pets and horses. HOECHST was acquired by INTERVET, now MERCK ANIMAL HEALTH.

Fenbendazole is a veteran benzimidazole introduced in the 1970s (by HOECHST). It is abundantly used in livestock an horses, moderately in pets. It is a broad-spectrum anthelmintic effective against most gastrointestinal worms that infect pets, including roundworms (Toxocara canisToxocara cati, Toxascaris leonina), hookworms (Ancylostoma spp, Uncinaria stenocephala) and whipworms (Trichuris vulpis), but also against lungworms (Aelurostrongylus abstrusus) and certain tapeworms (e.g. Taenia spp).

Fenbendazole as well as other benzimidazoles (e.g. febantel, albendazole, mebendazole, etc.) and tetrahydropyrimidines (e.g. pyrantel, morantel, etc.) have no residual effect, i.e. they act against the worms during a few hours after administration but are quickly metabolized and excreted. For this reason treatment must often be repeated for certain indications. This is in contrast with wormers containing macrocyclic lactones (e.g. milbemycin oxime, selamectin) that ensure protection against numerous roundworms during weeks after a single treatment.

In some countries the same product is also marketed under the trade name SAFE-GUARD.

For an overview and a list of the most popular pet wormers click here.


DISCLAIMER

This article IS NOT A PRODUCT LABEL. It offers complementary information that may be useful to veterinary professionals and users that are not familiar with veterinary antiparasitics. 

Information offered in this article has been extracted from publications issued by manufacturers, government agencies (e.g. EMEA, FDA, USDA, etc.) or in the scientific literature. No guarantee is given on its accuracy, integrity, sufficiency, actuality and opportunity, and any liability is denied. Read the site's DISCLAIMER.

In case of doubt contact the manufacturer or a veterinary professional.

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