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Brand: LOPATOL ®

Company: NOVARTIS


FORMULATION: «tablets» for oral administration;

ACTIVE INGREDIENT(S): NITROSCANATE 100 and 500 mg/tablet

CHEMICAL CLASS of the active ingredient(s): ISOTHIOCYANATE


INDICATIONS: DOGS

PARASITES CONTROLLED* (spectrum of activity):


RECOMMENDED DOSE*:

  • Dogs: minimum of 50 mg/kg bodyweight, which is equivalent to 1 x 100 mg tablet per 2 kg (4.4 lb) bodyweight or 1 x 500 mg tablet per 10 kg (22 lb) bodyweight.
  • To be administered in the morning after overnight fasting with approximately one-fifth of the daily food ration. The remaining food ration should be withheld for at least 8 hours.

* Can be slightly different in some countries: read the product label!


SAFETY

  • LD50 (acute oral) in rats: >5000 mg/kg for the active ingredient.
  • Estimated Hazard Class according to the WHO: not applicable for veterinary medicines

Suspected poisoning? Read the articles on nitroscanate safety in this site.

You may be interested in the following articles in this site dealing with the general safety of veterinary products:


RESISTANCE PREVENTION

Risk of resistance development? NO

There are no reports on resistance of dog worms to nitroscanate more than 40 years after its introduction.

Learn more about resistance and how it develops.


MARKETING

Are the active ingredients of this product ORIGINAL* or GENERICS**?

  • Nitroscanate: GENERIC (introduced in the 1970s)

*Meaning that they are still patent protected and generics are not yet available
**Meaning that they have lost patent protection and may be acquired from manufacturers of generic active ingredients other than the holder of the original patent.

COUNTRIES where this product is marketed: Some EU countries, Canada, Australia.
GENERIC BRANDS available? YES, in some countries.

Click here to learn more about GENERIC vs. ORIGINAL drugs.


COMMENTS

LOPATOL is an original brand from CIBA-GEIGY developed in the late 1970s (by CIBA-GEIGY → NOVARTIS → ELANCO).

Nitroscanate is a broad-spectrum anthelmintic effective against gastrointestinal roundworms  and tapeworms. Use has been moderate to low, particularly after the introduction of more modern dog wormers in the last two decades. It is neither used in livestock, nor in agriculture.

It is known that nitroscanate can cause vomit after administration.

For an overview and a list of the most popular pet wormers click here.


DISCLAIMER

This article IS NOT A PRODUCT LABEL. It offers complementary information that may be useful to veterinary professionals and users that are not familiar with veterinary antiparasitics. 

Information offered in this article has been extracted from publications issued by manufacturers, government agencies (e.g. EMEA, FDA, USDA, etc.) or in the scientific literature. No guarantee is given on its accuracy, integrity, sufficiency, actuality and opportunity, and any liability is denied. Read the site's DISCLAIMER.

In case of doubt contact the manufacturer or a veterinary professional.

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