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Brand: EXODUS ® PASTE

Company: BIMEDA


FORMULATION: «oral paste» in pre-charged syringes

ACTIVE INGREDIENT(S)pyrantel pamoate (=embonate): 43.90% (= 430 g/kg)

CHEMICAL CLASS of the active ingredient(s): tetrahydropyrimidine


INDICATIONS

HORSES & PONIES


PARASITES CONTROLLED* (spectrum of activity)

* Country-specific differences may apply: read the product label.


RECOMMENDED DOSE*

*Can be slightly different in some countries: read the product label!

  • USA: Single oral dose of 3 mg pyrantel base per lb of body weight (~6.6 mg/kg pyrantel base).
  • The 23.6 g syringe has four weight mark increments. The 47.2 g syringe has eight weight mark increments. Each weight mark indicates the recommended dose for 300 pounds of body weight. One-half 47.2 g syringe treats a 1200 lb horse.

SAFETY

LD50 (acute oral) in rats: >5000 mg/kg.

Estimated hazard class according to the WHO: not applicable for veterinary medicines

Suspected poisoning? Read the articles on pyrantel safety in this site.

Withholding periods (=withdrawal times) for meat (country-specific differences may apply: read the product label)

  • MEAT & OFFAL: USA: Do not use in horses intended for human consumption.

WARNING !!!: Never use on humans, dogs or cats

You may be interested in the following articles in this site dealing with the general safety of veterinary products:


RESISTANCE PREVENTION

Risk of resistance? YES

This means that if this product does not achieve the expected efficacy against the mentioned parasites, it may be due to resistance and not to incorrect use, which is usually the most frequent cause of product failure.

Alternative chemical classes/active ingredients to prevent resistance of gastrointestinal roundworms through product rotation:

These alternative products may not be available in all countries, or may not be available as oral pastes or gels.

Learn more about resistance and how it develops.


MARKETING

Are the active ingredients of this product ORIGINAL* or GENERICS**?

GENERICS

*Meaning that they are still patent protected and generics are not yet available
**Meaning that they have lost patent protection and may be acquired from manufacturers of generic active ingredients other than the holder of the original patent.

COUNTRIES where this product is marketed: USA
GENERIC BRANDS available? YES

Click here to learn more about GENERIC vs. ORIGINAL drugs.


COMMENTS

This product is a classic oral paste dewormer for horses from BIMEDA with generic pyrantel.

Pyrantel is a veteran tetrahydropyrimidine introduced in the 1970s (by PFIZER → ZOETIS) that is moderately used in horses, abundantly in pets, but rather scarcely in ruminants. It is a narrow-spectrum anthelmintic effective against roundworms and a few tapeworms in the gut, but not against those in other organs (e.g. the lungs, the skin, etc). It is also ineffective against gastric bots (Gasterophilus spp) or whatever external parasites. 

Pyrantel has no residual effect, i.e. it kills the parasites after administration but does not protect against reinfestations. In year-round control programs the recommended treatment interval is usually 4 to 6 weeks.

For an overview and a list of the most used oral paste & gel brands click here.


DISCLAIMER

This article IS NOT A PRODUCT LABEL. It offers complementary information that may be useful to veterinary professionals and users that are not familiar with veterinary antiparasitics. 

Information offered in this article has been extracted from publications issued by manufacturers, government agencies (e.g. EMEA, FDA, USDA, etc.) or in the scientific literature. No guarantee is given on its accuracy, integrity, sufficiency, actuality and opportunity, and any liability is denied. Read the site's DISCLAIMER.

In case of doubt contact the manufacturer or a veterinary professional.

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