Brand: FENPRAL Intestinal Worming Tablets for CATS
CHEMICAL CLASS of the active ingredient(s):
PARASITES CONTROLLED* (spectrum of activity):
- Roundworms (Toxocara cati, Toxascaris leonina), hookworms (Ancylostoma tubaeforme, Ancylostoma braziliense, Uncinaria stenocephala)
- Tapeworms (Dipylidium caninum, Taenia spp)
- Cats ≥2.5 kg bw ½ tablet (equivalent to ≥20 mg/kg pyrantel embonate, ≥5.0 mg/kg praziquantel)
- Cats 2.6 kg to 5 kg bw 1 tablet (equivalent to 38.5 to 20 mg/kg pyrantel embonate, 9.6 to 5.0 mg/kg praziquantel)
- Cats >5 kg bw 1 tablet for every 5 kg bw
* Can be slightly different in some countries: read the product label!
- LD50 (acute oral) in rats: n.a. for the tablets. >5000 mg/kg for pyrantel; 2840 mg/kg for praziquantel
- Estimated Hazard Class according to the WHO: not applicable for veterinary medicines
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Risk of resistance development? VERY LOW.
Are the active ingredients of this product ORIGINAL* or GENERICS**?
- Pyrantel: GENERIC (introduced in the 1960s)
- Praziquantel: GENERIC (introduced in the 1970s)
*Meaning that they are still patent protected and generics are not yet available
**Meaning that they have lost patent protection and may be acquired from manufacturers of generic active ingredients other than the holder of the original patent.
COUNTRIES where this product is marketed: AUSTRALIA
GENERIC BRANDS available? YES, in some countries.
Click here to learn more about GENERIC vs. ORIGINAL drugs.
Pyrantel is a narrow-spectrum anthelmintic belonging to the chemical class of the tetrahydropyrimidines that was introduced in the 1960s (by PFIZER → ZOETIS). It is effective against roundworms and a few tapeworms (depending on the dose) in the gut, but not against those in other organs (e.g. the lungs, the skin, etc). It controls the most important dog worms such as the roundworms Toxocara canis and Toxascaris leonina, the hookworms Ancylostoma caninum and Uncinaria stenocephala. It is used a lot in pets and horses but rarely in livestock. There are dozens of products for pets with generic pyrantel.
Praziquantel is a veteran isoquinoline anthelmintic introduced in the 1970s (by BAYER). It is still the most effective and most vastly used parasiticide against tapeworms, but without any efficacy against roundworms, fleas or ticks. Praziquantel adds efficacy against tapeworms (Dipylidium caninum, Taenia pisiformis, etc.) but has no efficacy whatsoever against roundworms, hookworms or whipworms. It is the anthelmintic most vastly used against tapeworms in pets. There are hundreds of antiparasitic brands for pets containing praziquantel.
Pyrantel and praziquantel have no residual effect, i.e. they act against the worms during a few hours after administration but are quickly metabolized and excreted. For this reason treatment must often be repeated for certain indications.
For an overview and a list of the most popular pet wormers click here.
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