Please enable / Bitte aktiviere JavaScript!
Veuillez activer / Por favor activa el Javascript![ ? ]

Dosing recommendations for antiparasitics depend on national regulations. National regulatory authorities determine whether a product is approved for a given indication, i.e. use on a particular host at a specific dose and against a specific parasiteCheck the labels of the products available in your country for specific information on approved indications.

The following table reproduces some usual dosing recommendations for abamectin issued by manufacturers or documented in the scientific literature. They may not be approved in some countries.

Abamectin is abundantly used in livestock in some regions (e.g. latin America, Australia), but rather scarcely in other regions (e.g. USA, EU). It is used mainly in pour-ons, drenches and injectables. It is both used alone or in combination with many other active ingredients. Use in pets is so far irrrelevant.

Abamectin is effective against roundworms (gastrointestinal, respiratory, renal, in the skin, etc.) and depending on the delivery form and the dosage also against a number of external parasites such as lice, mites and various myiasis. However, it is ineffective against tapeworms and flukes, and at the usual use recommendations it doesn't control e.g. fleas, stable flies, mosquitoes, horse flies, multi-host ticks (e.g. Amblyomma spp, Dermacentor spp, Haemaphysalis spp, Ixodes spp, Rhipicephalus spp, etc.) and several other external parasites. In the last years it has been increasingly used in some countries against cattle ticks (Boophilus = Rhipicephalus microplus) and horn flies (Haematobia irritans), but efficacy against these parasites is often mediocre and insufficient.

In most finished products, efficacy and safety depend not only on the amount of active ingredient(s) but also on their formulations (i.e. the type and amount of so-called inert ingredients), particularly in injectables and in topical pour-ons. These inert ingredients can significantly affect the pharmacokinetic behavior (e.g. absorption through the skin or from the injection site, distribution within the body, spreading throughout the body surface, etc.). Generic products usually contain the same amount of active ingredient(s) as the original product, but often in quite different formulations. In many cases, the curative (therapeutic) efficacy of the different formulations is quite comparable, but the protective (prophylactic) efficacy that determines the length of protection against re-infestations may be rather different.

Dosing recommendations for ABAMECTIN
CATTLE
Delivery Parasites   Dose (against abamectin-susceptible parasites)
Subcutaneous Roundworms 0.2 mg/kg. Covers most important cattle roundworms
Subcutaneous Screwworms 0.2 mg/kg. Mainly preventative use.
Subcutaneous Dermatobia hominis 0.2 mg/kg. About 4-6 weeks protection.
Subcutaneous Sarcoptes bovis 0,2 mg/kg
Subcutaneous Boophilus microplus 0.2 mg/kg. No knock-down effect. Control is usually incomplete (<85%). Residual effect <7 days, depending on the formulation.
Subcutaneous Lice (excep. Damalinis bovis) 0.2 mg/kg
Subcutaneous Hypoderma spp 0.2 mg/kg
Pour-on Roundworms 0.5 mg/kg. Covers most important cattle roundworms
Pour-on Mites 0.5 mg/kg. Needs 3-4 weeks for mites to disappear
Pour-on Boophilus microplus 0.5 mg/kg. No knock-down effect. Control is usually incomplete (<85%). Residual effect <7 days
Pour-on Haematobia irritans 0.5 mg/kg. Usually incomplete control (<80%), protection 3-4 weeks
Pour-on Lice 0.5 mg/kg. Lice-free animals only after about 1 week
Pour-on Dermatobia hominis 0.5 mg/kg. About 5 weeks protection
SHEEP & GOATS
Delivery Parasites Dose (against abamectin-susceptible parasites)
Drench Roundworms 0.2 mg/kg. Covers most important sheep roundworms
Subcutaneous Roundworms 0.2 mg/kg. Covers most important sheep roundworms
Subcutaneous  Oestrus ovis 0.2 mg/kg 
Subcutaneous Psoroptes ovis 0.2 mg/kg. Rep after 7 days
SWINE
Delivery Parasites Dose (against abamectin-susceptible parasites)
Subcutaneous Roundworms 0.3 mg/kg. Covers most important swine roundworms
Subcutaneous Sarcoptes scabiei 0.3 mg/kg
Subcutaneous Haematopinus suis 0.3 mg/kg
HORSES
Delivery Parasites Dose (against abamectin-susceptible parasites)
Oral (paste, gel) Roundworms 0.2 mg/kg. Covers most important horse roundworms
SOUTH AMERICAN CAMELIDS
Delivery Parasites Dose (against abamectin-susceptible parasites)
Subcutaneous Roundworms 0.2 mg/kg. Covers most important roundworms

DISCLAIMER: Liability is denied for any possible damage or harm to persons, animals or any other goods that could follow the transmission or use of the information, data or recommendations in this site by any site visitor or third parties.


  • Click here to view the technical summary of this active ingredient
  • Click here to view the safety summary of this active ingredient
  • Click here to view the list of all technical summaries of antiparasitic active ingredients in this site

Other articles in this site

GoogleCustom Search