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Brand: IMAX ® GOLD

Company: BAYER


FORMULATION: «oral paste» in pre-charged syringes

ACTIVE INGREDIENT(S):

CHEMICAL CLASS of the active ingredient(s):


INDICATIONS

HORSES

PARASITES CONTROLLED* (spectrum of activity)

* Country-specific differences may apply: read the product label.

  • Large Strongyles: Strongylus vulgaris (adults and arterial larval stages), Strongylus edentatus (both adult and tissue stages), Strongylus equinus (adults) and Triodontophorus spp (adults)
  • Small strongyles: Cyathostomum spp, Cylicocyclus spp, Cylicostephanus spp, Cylicodontophorus spp, Gyalocephalus spp, etc.
  • PinwormsOxyuris equi (adult and immature)
  • AscaridsParascaris equorum (adult and immature)
  • BotsGasterophilus spp (oral and gastric stages)
  • HairwormsTrichostrongylus axei (adult)
  • Intestinal Threadworms: Strongyloides westeri (adult)
  • Large Mouth Stomach WormsHabronema muscae (adult)
  • Lungworms: Dictyocaulus arnfieldi (adult and immature)
  • Small strongyles: Cyathostomum spp, Cylicocyclus spp, Cylicostephanus spp, Cylicodontophorus spp, Gyalocephalus spp.
  • TapewormsAnoplocephala perfoliataAnoplocephala magna, Paranoplocephala mamillana (adult, immature, heads, segments)
  • Controls also skin lesions caused by cutaneous larvae of Habronema and Draschia spp. (summer sores), and  Onchocerca spp microfilaraiae (cutaneous onchocerciasis)

RECOMMENDED DOSE*

*Can be slightly different in some countries: read the product label!

  • 1 mL product per 50 kg bodyweight, equivalent to 200 mcg ivermectin/kg bw, and 1.5 mg/kg praziquantel/kg bw.

SAFETY

  • LD50 (acute oral) in rats: ~2500 mg/kg (estimate calculated according to the WHO based on the ivermectin LD50)
  • Estimated hazard class according to the WHO: not applicable for veterinary medicines

Suspected poisoning? Read the articles on  ivermectin safety and/or praziquantel safety in this site.

Withholding periods (=withdrawal times) for meat & milk (country-specific differences may apply: read the product label)

  • MEAT & OFFAL: 28 days. ESI: Not required
  • MILK: Do not use in animals producing milk for human consumption

WARNING !!!: Never use on humans, dogs or cats

You may be interested in the following articles in this site dealing with the general safety of veterinary products:


RESISTANCE PREVENTION

Risk of resistance? YES

This means that if this product does not achieve the expected efficacy against the mentioned parasites, it may be due to resistance and not to incorrect use, which is usually the most frequent cause of product failure.

Alternative chemical classes/active ingredients to prevent resistance of gastrointestinal roundworms through product rotation:

These alternative products may not be available in all countries, or may not be available as oral drenches.

Learn more about resistance and how it develops.


MARKETING

Are the active ingredients of this product ORIGINAL* or GENERICS**?

  • GENERICS

*Meaning that they are still patent protected and generics are not yet available
**Meaning that they have lost patent protection and may be acquired from manufacturers of generic active ingredients other than the holder of the original patent.

COUNTRIES where this product is marketed: Australia
GENERIC BRANDS available? YES, by the dozens worldwide. This product itself contains generic ivermectin.

Click here to learn more about GENERIC vs. ORIGINAL drugs.


COMMENTS

This product is a classic oral drench for horses from BAYER with praziquantel and generic ivermectin.

Ivermectin was the first macrocyclic lactone introduced in the market in the early 1980s (by MSD Agvet, later MERIAL). It was a milestone and a tremendous progress that revolutionized the control of veterinary parasites. Nowadays there are thousands of brands with generic ivermectin worldwide. It is effective against most species of roundworms that affect horses and against bots (Gasterophilus spp), but not against tapeworms.

Ivermectin and other macrocyclic lactones have about two weeks residual effect on horses because they are stored in body fat and progressively released. This, together with the time that worms need to develop inside the horse after infection (pre-patent period) allows to space the treatment intervals to 10 to 12 weeks in year-round control programs in many regions. For other active ingredients that have no residual effect such as fenbendazolemebendazole, or pyrantel the treatment interval is usually 4 to 6 weeks.

Whereas in ruminants ivermectin administered at 200 mcg/kg controls a series of external parasites as well (mites, lice, etc.), such an indication is not approved in most countries in horses: external parasites have to be controlled with ectoparasiticides (e.g. pour-ons, sprays, etc.).

Praziquantel is a veteran anthelmintic introduced in the 1970s (by BAYER). It is highly effective against tapeworms (in horses mainly Anoplocephala spp) but has no efficacy whatsoever against roundworms. It is the anthelmintic most vastly used against tapeworms in horses and pets, used in hundreds of brands. It is hardly used in livestock. Praziquantel has no residual effect, i.e. it kills the parasites after administration but does not protect against reinfestation.

For an overview and a list of the most used oral drench brands click here.


DISCLAIMER

This article IS NOT A PRODUCT LABEL. It offers complementary information that may be useful to veterinary professionals and users that are not familiar with veterinary antiparasitics. 

Information offered in this article has been extracted from publications issued by manufacturers, government agencies (e.g. EMEA, FDA, USDA, etc.) or in the scientific literature. No guarantee is given on its accuracy, integrity, sufficiency, actuality and opportunity, and any liability is denied. Read the site's DISCLAIMER.

In case of doubt contact the manufacturer or a veterinary professional.

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