Brand: CAZITEL ® FLAVOURED TABLETS
CHEMICAL CLASS of the active ingredient(s):
PARASITES CONTROLLED* (spectrum of activity):
- Roundworms (Toxocara cati, Toxascaris leonina)
- Tapeworms (Dipylidium caninum, Taenia spp, Echinococcus multilocularis)
UK and other countries: 20 mg/kg bodyweight pyrantel (equivalent to 57.5 mg/kg pyrantel embonate) and 5 mg/kg praziquantel. This is equivalent to 1 tablet per 4 kg bodyweight. Tablets can be divided into equal halves to assist with accurate dosing.
- 1.0 to 2.0 kg: ½ tablet
- 2.1 to 4 kg: 1 tablet
- 4.1 to 6 kg: 1½ tablet
- 6.1 to 8.0 kg: 2 tablets
* Can be slightly different in some countries: read the product label!
- LD50 (acute oral) in rats: n.a. for the tablets. >5000 mg/kg for pyrantel; 2840 mg/kg for praziquantel
- Estimated Hazard Class according to the WHO: not applicable for veterinary medicines
Never use on cats tablets approved only for use on dogs, and vice-versa. Learn more about tablets and their safety.
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- Hazard classifications of pesticides
Risk of resistance development? NO
Are the active ingredients of this product ORIGINAL* or GENERICS**?
- Pyrantel: GENERIC (introduced in the 1960s)
- Praziquantel: GENERIC (introduced in the 1970s)
*Meaning that they are still patent protected and generics are not yet available
**Meaning that they have lost patent protection and may be acquired from manufacturers of generic active ingredients other than the holder of the original patent.
COUNTRIES where this product is marketed: UK and other EU countries.
GENERIC BRANDS available? YES, in many countries.
Click here to learn more about GENERIC vs. ORIGINAL drugs.
Pyrantel is a narrow-spectrum anthelmintic belonging to the chemical class of the tetrahydropyrimidines that was introduced in the 1960s (by PFIZER → ZOETIS). It is effective against roundworms and a few tapeworms (depending on the dose) in the gut, but not against those in other organs (e.g. the lungs, the skin, etc). It controls important dog worms such as the roundworms Toxocara canis and Toxascaris leonina, the hookworms Ancylostoma caninum and Uncinaria stenocephala. It is used a lot in pets and horses but rarely in livestock. There are dozens of products for pets with generic pyrantel.
Praziquantel is a veteran isoquinoline anthelmintic introduced in the 1970s (by BAYER). It is still the most effective and most vastly used parasiticide against tapeworms, but without any efficacy against roundworms, fleas or ticks. Praziquantel adds efficacy against tapeworms (e.g. Dipylidium caninum, Taenia pisiformis, Echinococcus spp) but has no efficacy whatsoever against roundworms, hookworms or whipworms. It is the anthelmintic most vastly used against tapeworms in pets. There are hundreds of antiparasitic brands for pets containing praziquantel.
Pyrantel and praziquantel have no residual effect, i.e. they act against the worms during a few hours after administration but are quickly metabolized and excreted. For this reason treatment must often be repeated for certain indications. This is in contrast with wormers containing macrocyclic lactones (e.g. milbemycin oxime, selamectin) that ensure efficacy against numerous roundworms during weeks after a single treatment.
For an overview and a list of the most popular pet wormers click here.
This article IS NOT A PRODUCT LABEL. It offers complementary information that may be useful to veterinary professionals and users that are not familiar with veterinary antiparasitics.
Information offered in this article has been extracted from publications issued by manufacturers, government agencies (e.g. EMEA, FDA, USDA, etc.) or in the scientific literature. No guarantee is given on its accuracy, integrity, sufficiency, actuality and opportunity, and any liability is denied. Read the site's DISCLAIMER.
In case of doubt contact the manufacturer or a veterinary professional.