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Common name: DICHLOROPHEN (Antiphen, Triclosan)

Type: veterinary medecine
Chemical class: phenol derivative

CHEMICAL STRUCTURE

Molecular structure of PIPERAZINE 

 


EFFICACY AGAINST PARASITES

Type of action: narrow-spectrum anthelmintic, endoparasiticide
Main veterinary parasites controlled: selected gastrointestinal tapeworms (= taenicide, cestodicide)

Efficacy against a specific parasite depends on the delivery form and on the dose administered.

Click here for general information on features and characteristics of PARASITICIDES.


DOSING

Dosing recommendations for antiparasitics depend on national regulations.

National regulatory authorities determine whether a product is approved for a given indication, i.e. use on a particular host at a specific dose and against a specific parasite.

Check the labels of the products available in your country for specific information on approved indications.


SAFETY

Oral LD50, rat, acute*: 2600 mg/kg
Dermal LD50, rat, acute*: not found
* These values refer to the active ingredient. Toxicity has to be determined for each formulation as well. Formulations are usually significantly less toxic than the active ingredients.

Not used in food producing animals, only in pets

* This information is an indicator of the acceptance of an active ingredient by the most influential regulatory bodies for use on livestock.

General information on the safety of veterinary antiparasitics is available in specific articles in this site (click to visit):

WARNING

Never use products for livestock on dogs and cats unless they are explicitly approved for both livestock and pets. Pets may not tolerate livestock formulations

It is obvious that veterinary products are not intended for and should never be used on humans!!!


MARKETING & USAGE

Decade of introduction: ~1950
Introduced by: ?
Some brands: PANACIDE, TENIATOL
Patent: Expired (particular formulations may be still patent-protected)

Use in LIVESTOCK: No
Use in HORSES: ?
Use in DOGS and CATS: Yes, very scarce

Main delivery forms: 

Use in human medicine. YES
Use in public/domestic hygiene: No
Use in agriculture: No
Generics available:  Yes, a few


PARASITE RESISTANCE

On livestock & horses: No
On dogs and cats: No

Learn more about parasite resistance and how it develops.


SPECIFIC FEATURES

Dichlorphen is one of the oldest anthelmintics used in veterinary and human medicine (introduced in the 1940s). It is a narrow-spectrum taenicide effective particularly against large tapeworms (e.g. Taenia solium, Taenia saginata, etc.). It has also bactericidal, algicidal and fungicidal properties.

Dichlorophen is used both in human and veterinary medicine. But nowadays veterinary use is irrelevant, only in a few pet wormers, not in livestock. It has been vastly replaced by more modern and effectice compounds. It is also used as a preserving agent in the cosmetic, food, textile and other industries.

Click here to view the list of all technical summaries of antiparasitic active ingredients in this site.

Other articles in this site

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