Brand: PARAZOLE 10% w/v Oral Suspension

Company: MSD ANIMAL HEALTH


FORMULATION: oral suspension

ACTIVE INGREDIENT(S): FENBENDAZOLE 10% w/v  (=100 mg/mL)

CHEMICAL CLASS of the active ingredient(s): BENZIMIDAZOLE


INDICATIONS: DOGS and CATS


PARASITES CONTROLLED* (spectrum of activity):

  • For the treatment of domestic dogs and cats infected with immature and mature stages of nematodes of the gastrointestinal and respiratory tracts.
  • Effective against immature and mature ascarids, hookworms and tapeworms.
  • Also kills roundworm eggs.

RECOMMENDED DOSE*:

Ireland:

  • Dose for routine worming:
    • Shake well before use and administer a single dose at a dose rate of 100 mg/kg bodyweight which is equivalent to 1 ml per 1 kg body weight.
  • Dose rate for weaned puppies and kittens under six months of age and lungworms in cats
    • Shake well before use and administer a single dose for 3 consecutive days at a rate of 50 mg/kg body weight which is equivalent to 1 ml per 2kg body weight.
    • Puppies should be treated at 2 weeks of age, 5 weeks of age and again before leaving the breeder’s premises. Treatment may also be required at 8 weeks and 12 weeks of age.
    • Thereafter, frequency of treatment can be reduced unless the pups remain in kennels where reinfestation occurs more readily.
  • Dose rate for pregnant bitches:
    • Shake well before use and administer 1ml per 4 kg body weight daily from day 40 of pregnancy continuously for approximately 25 days. This is equivalent to 25 mg fenbendazole /kg body weight daily.
  • For oral administration only.
  • Fenbendazole can be administered orally either directly into the mouth or alternatively it can be mixed in feed. Good mixing of the product in feed is advisable.

* Can be slightly different in some countries: read the product label!


SAFETY

  • LD50 (acute oral) in rats: >10000 mg/kg for fenbendazole a.i.
  • Estimated Hazard Class according to the WHO: not applicable for veterinary medicines

Suspected poisoning? Read the articles on fenbendazole safety in this site.

You may be interested in the following articles in this site dealing with the general safety of veterinary products:


RESISTANCE PREVENTION

Risk of resistance development? NO


MARKETING

Are the active ingredients of this product ORIGINAL* or GENERICS**?

Fenbendazole: GENERIC (introduced in the 1970s)

*Meaning that they are still patent protected and generics are not yet available
**Meaning that they have lost patent protection and may be acquired from manufacturers of generic active ingredients other than the holder of the original patent.

COUNTRIES where this product is marketed: Ireland
GENERIC BRANDS available? YES, in most countries, perhaps not with the same formulation. This brand contains itself generic fenbendazole.

Click here to learn more about GENERIC vs. ORIGINAL drugs.


COMMENTS

PARAZOLE 10% w/v Oral Suspension is a classic dog wormer from FORAN with generic fenbendazole.

Fenbendazole is a veteran benzimidazole introduced in the 1970s (by HOECHST). It is a broad-spectrum anthelmintic effective against most gastrointestinal worms that infect pets, including roundworms (Toxocara canisToxocara cati, Toxascaris leonina), hookworms (Ancylostoma spp, Uncinaria stenocephala) and whipworms (Trichuris vulpis), but also against lungworms (Aelurostrongylus abstrusus) and certain tapeworms (e.g. Taenia spp). It is abundantly used in livestock and horses, moderately in pets. It is not used in agriculture.

Fenbendazole an most other benzimidazoles (e.g. febantel, albendazole, mebendazole, etc.) and tetrahydropyrimidines (e.g. pyrantel, morantel, etc.) have no residual effect, i.e. they act against the worms during a few hours after administration but are quickly metabolized and excreted. For this reason treatment must often be repeated for certain indications. This is in contrast with wormers containing macrocyclic lactones (e.g. milbemycin oxime, selamectin) that ensure protection against numerous roundworms during weeks after a single treatment.

For an overview and a list of the most popular pet wormers click here.


DISCLAIMER

This article IS NOT A PRODUCT LABEL. It offers complementary information that may be useful to veterinary professionals and users that are not familiar with veterinary antiparasitics. 

Information offered in this article has been extracted from publications issued by manufacturers, government agencies (e.g. EMEA, FDA, USDA, etc.) or in the scientific literature. No guarantee is given on its accuracy, integrity, sufficiency, actuality and opportunity, and any liability is denied. Read the site's DISCLAIMER.

In case of doubt contact the manufacturer or a veterinary professional.

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