Brand: EXODUS ® PASTE
HORSES & PONIES
PARASITES CONTROLLED* (spectrum of activity)
* Country-specific differences may apply: read the product label.
- Control and treatment of adult infections of large strongyles and small strongyles, Oxyuris, Parascaris and Anoplocephala perfoliata.
*Can be slightly different in some countries: read the product label!
- USA: Single oral dose of 3 mg pyrantel base per lb of body weight (~6.6 mg/kg pyrantel base).
- The 23.6 g syringe has four weight mark increments. The 47.2 g syringe has eight weight mark increments. Each weight mark indicates the recommended dose for 300 pounds of body weight. One-half 47.2 g syringe treats a 1200 lb horse.
LD50 (acute oral) in rats: >5000 mg/kg.
Estimated hazard class according to the WHO: not applicable for veterinary medicines
Suspected poisoning? Read the articles on pyrantel safety in this site.
Withholding periods (=withdrawal times) for meat (country-specific differences may apply: read the product label)
- MEAT & OFFAL: USA: Do not use in horses intended for human consumption.
WARNING !!!: Never use on humans, dogs or cats
You may be interested in the following articles in this site dealing with the general safety of veterinary products:
- Safety for humans
- Safety for domestic animals
- Safety for the environment
- Hazard classifications of pesticides
Risk of resistance? YES
- Parascaris equorum: Cases of resistance to pyrantel have been reported (e.g. in Europe, the USA and Brazil).
- Small strongyles (cyathostomes): Cases of resistance to pyrantel have been reported (e.g. in the EU, USA and Canada).
This means that if this product does not achieve the expected efficacy against the mentioned parasites, it may be due to resistance and not to incorrect use, which is usually the most frequent cause of product failure.
- Benzimidazoles, mainly fenbendazole, mebendazole, etc. But they also have similar or even worse resistance problems than pyrantel
- Imidazothiazoles, mainly levamisole. Not approved for use in horses in many countries.
- Macrocyclic lactones: mainly ivermectin, moxidectin. But tolerance or resistance to these compounds have also been reported in Europe (e.g. in the UK, Germany, Italy), the USA, and Brazil.
These alternative products may not be available in all countries, or may not be available as oral pastes or gels.
Are the active ingredients of this product ORIGINAL* or GENERICS**?
*Meaning that they are still patent protected and generics are not yet available
**Meaning that they have lost patent protection and may be acquired from manufacturers of generic active ingredients other than the holder of the original patent.
COUNTRIES where this product is marketed: USA
GENERIC BRANDS available? YES
Click here to learn more about GENERIC vs. ORIGINAL drugs.
This product is a classic oral paste dewormer for horses from BIMEDA with generic pyrantel.
Pyrantel is a veteran tetrahydropyrimidine introduced in the 1970s (by PFIZER → ZOETIS) that is moderately used in horses, abundantly in pets, but rather scarcely in ruminants. It is a narrow-spectrum anthelmintic effective against roundworms and a few tapeworms in the gut, but not against those in other organs (e.g. the lungs, the skin, etc). It is also ineffective against gastric bots (Gasterophilus spp) or whatever external parasites.
For an overview and a list of the most used oral paste & gel brands click here.
This article IS NOT A PRODUCT LABEL. It offers complementary information that may be useful to veterinary professionals and users that are not familiar with veterinary antiparasitics.
Information offered in this article has been extracted from publications issued by manufacturers, government agencies (e.g. EMEA, FDA, USDA, etc.) or in the scientific literature. No guarantee is given on its accuracy, integrity, sufficiency, actuality and opportunity, and any liability is denied. Read the site's DISCLAIMER.
In case of doubt contact the manufacturer or a veterinary professional.