Brand: Tasty Intestinal Allwormer Tablets for Cats & Kittens

Company: PURINA


FORMULATION: «tablets» for oral administration; may be chewable, flavored, coated, etc.

ACTIVE INGREDIENT(S):

  • MILBEMYCIN OXIME:
    • For kittens & small cats: 4 mg
    • For larger cats >2 kg: 16 mg
  • PRAZIQUANTEL: 10 mg
    • For kittens & small cats: 10 mg
    • For larger cats >2 kg: 40 mg

CHEMICAL CLASS of the active ingredient(s):


INDICATIONS: CATS

PARASITES CONTROLLED* (spectrum of activity):


RECOMMENDED DOSE*:

  • Cats 0.5 to 1 kg bw: ½ tablet for small cats (4 to 2 mg/kg milbemycin oxime, 10 to 5 mg/kg praziquantel mg/kg praziquantel)
  • Cats >1 to 2 kg bw: 1 tablet for small cats (4 to 2 mg/kg milbemycin oxime, 10 to 5 mg/kg praziquantel mg/kg praziquantel)
  • Cats >2 to 4 kg bw: ½ tablet for larger cats (4 to 2 mg/kg milbemycin oxime, 10 to 5 mg/kg praziquantel mg/kg praziquantel)
  • Cats >4 to 8 kg bw: 1 tablet for larger cats (4 to 2 mg/kg milbemycin oxime, 10 to 5 mg/kg praziquantel mg/kg praziquantel)
  • Cats > 8 kg: a combination of tablets should be given consistent with the recommended minimum dose (2 mg/kg milbemycin oxime, 5 mg/kg praziquantel)

* Can be slightly different in some countries: read the product label!


SAFETY

  • LD50 (acute oral) in rats: n.a. for the tablets. 980 mg/kg for the a.i. milbemycin oxime a.i., and 2000 - 3000 mg/kg for praziquantel a.i.
  • Estimated Hazard Class according to the WHO: not applicable for veterinary medicines

Suspected poisoning? Read the article on milbemycin oxime safety and/or on praziquantel safety in this site.

You may be interested in the following articles in this site dealing with the general safety of veterinary products:


RESISTANCE PREVENTION

Risk of resistance development? VERY LOW

There are so far no reports on resistance of roundworms to milbemycin oxime or of tapeworms to praziquantel in cats.

Learn more about resistance and how it develops.


MARKETING

Are the active ingredients of this product ORIGINAL* or GENERICS**?

  • Milbemycin oxime: GENERIC (introduced in the 1980s)
  • Praziquantel: GENERIC (introduced in the 1970s)

*Meaning that they are still patent protected and generics are not yet available
**Meaning that they have lost patent protection and may be acquired from manufacturers of generic active ingredients other than the holder of the original patent.

COUNTRIES where this product is marketed: AUSTRALIA
GENERIC BRANDS available? YES, in some countries.

Click here to learn more about GENERIC vs. ORIGINAL drugs.


COMMENTS

Tasty Intestinal Allwormer Tablets for Cats & Kittens from PURINA is a generic wormer effective against roundworms and tapeworms

Milbemycin oxime is a macrocyclic lactone effective against roundworms and some external parasites that was introduced in the late 1980s (by CIBA-GEIGY → NOVARTIS → ELANCO). It is exclusively used in pets, not in livestock, horses or agriculture. As a general rule, due to a different pharmacokinetic behavior the anthelmintic effect is longer for milbemycin oxime than for ivermectin, although this strongly depends on the delivery form and the administered dose. Milbemicin oxime controls several cat roundworms (Toxocara cati, Toxascaris leonina) and hookworms (Ancylostoma tubaeformae), but not tapeworms.

Praziquantel is a veteran isoquinoline anthelmintic introduced in the 1970s (by BAYER). It is still the most effective and most vastly used parasiticide against tapeworms, but without any efficacy against roundworms, fleas or ticks. Praziquantel adds efficacy against tapeworms (e.g. Dipylidium caninum, Taenia spp) but has no efficacy whatsoever against roundworms, hookworms or whipworms. It is the anthelmintic most vastly used against tapeworms in pets. There are hundreds of antiparasitic brands for pets containing praziquantel.

Praziquantel has no residual effect, i.e. it acts against the worms during a few hours after administration but is quickly metabolized and excreted. For this reason treatment may have to be repeated for certain indications.

For an overview and a list of the most popular pet wormers click here.


DISCLAIMER

This article IS NOT A PRODUCT LABEL. It offers complementary information that may be useful to veterinary professionals and users that are not familiar with veterinary antiparasitics. 

Information offered in this article has been extracted from publications issued by manufacturers, government agencies (e.g. EMEA, FDA, USDA, etc.) or in the scientific literature. No guarantee is given on its accuracy, integrity, sufficiency, actuality and opportunity, and any liability is denied. Read the site's DISCLAIMER.

In case of doubt contact the manufacturer or a veterinary professional.