Brand: FLUBENVET ® 5% w/w Premix
Company: ELANCO
DELIVERY FORM: «feed additives and medicated feeds» for oral administration. For incorporation into dry feed at a registered mill.
ACTIVE INGREDIENT(S): flubendazole 50 ml/L (equivalent to 5%)
CHEMICAL CLASS of the active ingredient(s): benzimidazole
INDICATIONS: POULTRY, CHICKENS, TURKEY, GAME BIRDS
PARASITES CONTROLLED (spectrum of activity)*
- Mature and immature stages and eggs of the following nematodes of chickens, turkeys, geese, partridges and pheasants:
- In the gastrintestinal tract: Ascaridia galli (large roundworm), Heterakis gallinarum (caecal worm), Capillaria spp (hair worm), Amidostomum anseris (gizzard worm), Trichostrongylus tenuis.
- In the respiratory tract: Syngamus trachea (gapeworm).
* Country-specific differences may apply: read the product label.
RECOMMENDED DOSE*
- Pheasants and partridges: 1.2 kg product is incorporated into 1 tonne of feeding stuff to provide 60g flubendazole per tonne of feed (60 mg/kg = 60 ppm). Treat for 7 consecutive days.
- Chickens and geese: 600 g product is incorporated into 1 tonne of feeding stuff to provide 30 g flubendazole is incorporated into 1 tonne of feed (30 mg/kg = 30 ppm). Treat for 7 consecutive days.
- Turkeys: 400 g product is incorporated into 1 tonne of feeding stuff to provide 20 g flubendazole per tonne of feed. (20 mg/kg = 20 ppm). Treat for 7 consecutive days.
Read the product label for additional use recommendations.
* Country-specific differences may apply: read the product label.
SAFETY
- LD50 (acute oral) in rats: >5000 mg/kg (for the a.i.)
- LD50 (acute dermal) in rats: n.a.
Suspected poisoning? Read the article on flubendazole safety in this site.
Withholding periods (=withdrawal times) in days for meat & eggs (country-specific differences may apply: read the product label)
- Meat: 7 days
- Eggs: NIL
WARNING !!!: Never use on humans, dogs or cats
You may be interested in the following articles in this site dealing with the general safety of veterinary products:
- Safety for humans
- Safety for domestic animals
- Safety for the environment
- Hazard classifications of pesticides
RESISTANCE PREVENTION
There are no reports on resistance of poultry roundworms to benzimidazoles more than 40 years after their introduction for this use.
This means that if this product does not achieve the expected efficacy against the mentioned parasites, it is most likely that it is not due to resistance but to incorrect use, which is the most frequent cause of product failure.
However, to prevent or at least delay resistance development it is a good practice to periodically alternate anthelmintics (rotation) with different modes of action.
Alternative chemical classes/active ingredients to prevent resistance of gastrointestinal roundworms through product rotation in poultry:
- Levamisole.
- Piperazine. Effective only against certain gastrointestinal roundworms (mainly ascarids).
These alternative products may not be available in all countries or may not be effective against all the concerned parasites.
It is highly recommended to periodically check the resistance status of each property performing appropriate tests (e.g. fecal egg counts) under supervision of a veterinary doctor.
Learn more about resistance and how it develops.
MARKETING
Are the active ingredients of this product ORIGINAL* or GENERICS**?
- GENERICS
*Meaning that they are still patent protected and generics are not yet available
**Meaning that they have lost patent protection and may be acquired from manufacturers of generic active ingredients other than the holder of the original patent.
COUNTRIES where this brand/product is marketed: UK and other EU countries
GENERIC BRANDS available? Yes, in some countries, but not too many.
Click here to learn more about GENERIC vs. ORIGINAL drugs.
Click here for an overview on the most used antiparasitic feed additives and medicated feeds for livestock and horses.
COMMENTS
FLUBENVET 5% w/w Premix is a classic anthelmintic for poultry from ELANCO containing generic flubendazole.
Flubendazole is a veteran anthelmintic introduced in the 1970s (by JANSSEN). It has a broad-spectrum of activity against roundworms (gastrointestinal and pulmonary) but is ineffective against tapeworms and flukes. Flubendazole also kills eggs of roundworms (ovicidal activity). As all benzimidazoles, flubendazole has no efficacy whatsoever against external parasites (ticks, flies, lice, mites, etc). Among the benzimidazoles flubendazole is quite comparable with mebendazole in terms of efficacy and safety. Flubendazole is moderately used in pig & poultry but rather scarcely in ruminants, horses or pets. It is not used in agriculture.
As all benzimidazoles (as well as other anthelmintics such as levamisole and tetrahydropyrimidines), flubendazole has no residual effect, i.e. it kills the parasites shortly after administration, but as soon as medicated feeding is interrupted it does not significantly protect the animals against re-infestation by infective stages in their environment.
DISCLAIMER
This article IS NOT A PRODUCT LABEL. It offers complementary information that may be useful to veterinary professionals and users that are not familiar with veterinary antiparasitics.
Information offered in this article has been extracted from publications issued by manufacturers, government agencies (e.g. EMEA, FDA, USDA, etc.) or in the scientific literature. No guarantee is given on its accuracy, integrity, sufficiency, actuality and opportunity, and any liability is denied. Read the site's DISCLAIMER.
In case of doubt contact the manufacturer or a veterinary professional.