Brand: ZANTEL ® Cat & Dog Tablets
Company: CHANELLE
FORMULATION: «tablets» for oral administration; may be chewable, flavored, coated, etc.
- FENBENDAZOLE: 500 mg/tablet
- PRAZIQUANTEL: 50 mg/tablet
CHEMICAL CLASS of the active ingredient(s):
- Fenbendazole: BENZIMIDAZOLE
- Praziquantel: ISOQUINOLINE
INDICATIONS*: DOGS & CATS
PARASITES CONTROLLED* (spectrum of activity):
Treatment of mixed infections of gastrointestinal nematodes and cestodes in dogs and cats.
- Ascarids: Toxocara cati (adult), Toxascaris leonina (immature, adult)
- Hookworms: Uncinaria stenocephala (immature, adult), Ancylostoma caninum (immature, adult)
- Whipworms Trichuris vulpis (adult)
- Tapeworms: Echinococcus granulosus, Echinococcus multilocularis, Dipylidium caninum, Taenia spp, Mesocestoides spp
May also be used as an aid in the control of Giardia protozoa in dogs and Aelurostrongylus abstrusus lungworm infection in cats.
* Can be slightly different in some countries: read the product label!
RECOMMENDED DOSE*:
- Routine treatment of adult dogs: Zantel Cat and Dog should be administered as a single treatment at a dose rate of 5 mg praziquantel and 50 mg fenbendazole per kg bw (equivalent to 1 tablet per 10 kg bw).
- Routine treatment of adult cats: Zantel Cat and Dog should be administered as a single treatment at a dose rate of 5 mg praziquantel and 50 mg fenbendazole per kg bw(equivalent to ½ tablet per 5 kg bw).
- For routine control adult dogs and cats should be treated once every 3 months.
- Weaned puppies & kittens under 6 months of age: Zantel Cat and Dog should be administered at a dose rate of 5 mg praziquantel and 50 mg fenbendazole per kg bw (equivalent to ½ tablet per 5 kg bodyweight). Treatment should be administered for three consecutive days.
- Unweaned puppies and nursing bitches: For the control of Toxocara, it is important to worm young puppies very regularly with Zantel Cat and Dog, at a dose rate of 5 mg praziquantel and 50 mg fenbendazole per kg bodyweight daily for three consecutive days (equivalent to ½ tabletper 5 kg daily for 3 days). This treatment regimen should be repeated at 2 weekly intervals from the age of 2 weeks for pups less than 12 weeks of age. It is then recommended that Zantel Cat and Dog be administered at intervals of 3 months.
- Nursing bitches should be treated at the same time and as frequently as puppies up to 12 weeks of age. Thereafter the adult worming regime of once every three months is recommended.
- Increased dosing for specific infections
- For the treatment of Clinical worm infestation in adult dogs administer Zantel Cat and Dog at a dose rate of:-5 mg praziquantel and 50 mg fenbendazole per kg bw daily for two consecutive days (equivalent to 1 tablet per 10 kg daily for 2 days).
- For the treatment of Clinical worm infestations in adult cats and as an aid in the control of the lungworm Aelurostrongylus abstrusus in cats and Giardia protozoa in dogs administer Zantel Cat and Dog at a dose rate of 5 mg praziquantel and 50 mg fenbendazole per kg bodyweight daily for three consecutive days (equivalent to ½ tablet per 5 kg daily for 3 days).
Zantel Cat and Dog tablets are administered orally either directly or mixed with a portion of meat or sausage or mixed with food. Dietary measures or fasting are not necessary. Absorption may be improved with food.
* Can be slightly different in some countries: read the product label!
SAFETY
- LD50 (acute oral) in rats: n.a. for the tablets. >5000 mg/kg mg/kg for fenbendazole; 2840 mg/kg for praziquantel
- Estimated Hazard Class according to the WHO: not applicable for veterinary medicines
Suspected poisoning? Read the articles on fenbendazole safety and/or praziquantel safety in this site.
You may be interested in the following articles in this site dealing with the general safety of veterinary products:
- Safety for humans
- Safety for domestic animals
- Safety for the environment
- Hazard classifications of pesticides
RESISTANCE PREVENTION
Risk of resistance development? VERY LOW
- There are no reports on resistance of dog or cat roundworms to fenbendazole or other benzimidazoles.
- There are no reports on resistance of pet tapeworms to praziquantel.
Learn more about resistance and how it develops.
MARKETING
Are the active ingredients of this product ORIGINAL* or GENERICS**?
- Fenbendazole: GENERIC (introduced in the 1970s)
- Praziquantel: GENERIC (introduced in the 1970s)
*Meaning that they are still patent protected and generics are not yet available
**Meaning that they have lost patent protection and may be acquired from manufacturers of generic active ingredients other than the holder of the original patent.
COUNTRIES where this product is marketed: Ireland
GENERIC BRANDS available? YES, in some countries. This product itself contains generic active ingredients.
Click here to learn more about GENERIC vs. ORIGINAL drugs.
COMMENTS
ZANTEL Cat & Dog Tablets is a generic wormer effective against roundworms and tapeworms from CHANELLE.
Fenbendazole is a broad-spectrum anthelmintic belonging to the chemical class of the benzimidazoles that was introduced in the 1970s (by HOECHST → INTERVET → MSD ANIMAL HEALTH). It is a broad-spectrum anthelmintic effective against roundworms (e.g. Toxocara canis, Toxascaris leonina), hookworms (e.g. Ancylostoma caninum, A. braziliense, Uncinaria stenocephala), and whipworms (Trichuris vulpis). Depending on the dose it is also effective against some tapeworms. Fenbendazole is not very frequently used in pets, but a lot in horses and livestock, particularly in ruminants. It is not used in agriculture.
Praziquantel is a veteran isoquinoline anthelmintic introduced in the 1970s (by BAYER). It is still the most effective and most vastly used parasiticide against tapeworms, but without any efficacy against roundworms, fleas or ticks. Praziquantel adds efficacy against tapeworms (Dipylidium caninum, Taenia pisiformis, etc.). It is the anthelmintic most vastly used against tapeworms in pets. There are hundreds of antiparasitic brands for pets containing praziquantel. It is also used a lot in horses, but very scarcely in ruminants. It is not used in agriculture.
Fenbendazole and praziquantel have no residual effect, i.e. they act against the worms during a few hours after administration but are quickly metabolized and excreted. For this reason treatment must often be repeated for certain indications.
For an overview and a list of the most popular pet wormers click here.
DISCLAIMER
This article IS NOT A PRODUCT LABEL. It offers complementary information that may be useful to veterinary professionals and users that are not familiar with veterinary antiparasitics.
Information offered in this article has been extracted from publications issued by manufacturers, government agencies (e.g. EMEA, FDA, USDA, etc.) or in the scientific literature. No guarantee is given on its accuracy, integrity, sufficiency, actuality and opportunity, and any liability is denied. Read the site's DISCLAIMER.
In case of doubt contact the manufacturer or a veterinary professional.