Brand: ANTHELCIDE ® EQ
FORMULATION: «oral paste» in pre-charged syringes
ACTIVE INGREDIENT(S): oxibendazole: 22.7% (= 227 g/kg)
CHEMICAL CLASS of the active ingredient(s): benzimidazole
PARASITES CONTROLLED* (spectrum of activity)
* Country-specific differences may apply: read the product label.
- Removal and control of: large strongyles (Strongylus edenatus, S. equinus, S. vulgaris); small strongyles (species of the genera Cylicostephanus, Cylicocyclus, Cyathostomum, Triodontophorus, Cylicodontophorus, and Gyalocephalus); large roundworms (Parascaris equorum); pinworms (Oxyuris equis) including various larval stages; and threadworms (Strongyloides westeri).
*Can be slightly different in some countries: read the product label!
- 10 mg/kg (2.2 lb) of body weight (15 mg/kg for Strongyloides).
- Each mark on the syringe delivers Anthelcide EQ to treat 100 lb (67 lb for Strongyloides).
- Horses maintained on premises where reinfection is likely to occur should be retreated in 6-8 weeks.
- LD50 (acute oral) in rats: >5000 mg/kg (estimate calculated according to the WHO based on the LD50)
- Estimated hazard class according to the WHO: not applicable for veterinary medicines
Withholding periods (=withdrawal times) for meat & milk (country-specific differences may apply: read the product label)
- MEAT & OFFAL: US: Do not use in horses intended for human consumption
- MILK: Do not use in mares producing milk for human consumption.
Suspected poisoning? Read the article on oxfendazole safety in this site.
WARNING !!!: Never use on humans, dogs or cats
You may be interested in the following articles in this site dealing with the general safety of veterinary products:
- Safety for humans
- Safety for domestic animals
- Safety for the environment
- Hazard classifications of pesticides
Risk of resistance? YES
- Small strongyles (cyathostomes). Resistance of small strongyles to benzimidazoles is widespread and frequent e.g. in the USA, UK and Europe, Argentina, Chile, Uruguay, etc.
- Parascaris equorum: Cases of tolerance to benzimidazoles have been also reported (e.g. in the USA).
This means that if this product does not achieve the expected efficacy against the mentioned parasites, it may be due to resistance and not to incorrect use, which is usually the most frequent cause of product failure.
Alternative chemical classes/active ingredients to prevent resistance of gastrointestinal roundworms through product rotation:
- Imidazothiazoles, mainly levamisole. Not approved for use in horses in many countries.
- Macrocyclic lactones: mainly ivermectin, moxidectin. But tolerance or resistance to these compounds have also been reported in Europe (e.g. in the UK, Germany, Italy), the USA, and Brazil.
- Tetrahydropyrimidines, mainly pyrantel (limited spectrum of activity), but resistance cases have also been reported (e.g. Australia, USA, Brazil, Japan).
These alternative products may not be available in all countries, or may not be available as oral pastes or gels.
Learn more about resistance and how it develops.
Are the active ingredients of this product ORIGINAL* or GENERICS**?
*Meaning that they are still patent protected and generics are not yet available
**Meaning that they have lost patent protection and may be acquired from manufacturers of generic active ingredients other than the holder of the original patent.
COUNTRIES where this product is marketed (maybe under another TM): US and many other countries, but maybe a different formulation.
GENERIC BRANDS available? YES, but not in all countries
Click here to learn more about GENERIC vs. ORIGINAL drugs.
This product is a classic oral paste dewormer for horses from ZOETIS with original oxibendazole.
Oxibendazole is a veteran benzimidazole introduced in the 1970s (by SMITH KLINE → PFIZER→ ZOETIS) that is rather scarcely used in horses and ruminants. It is a broad-spectrum anthelmintic effective against roundworms in the gut and the lungs, but not against those in the skin. It is also ineffective against gastric bots (Gasterophilus spp) or whatever external parasites. At the recommended dose it is also ineffective against horse tapeworms (Anoplocephala spp). It is scarcely to moderately used in pets and horses. Usage is insignificant in livestock. It is not used in agriculture.
For an overview and a list of the most used oral paste & gel brands click here.
This article IS NOT A PRODUCT LABEL. It offers complementary information that may be useful to veterinary professionals and users that are not familiar with veterinary antiparasitics.
Information offered in this article has been extracted from publications issued by manufacturers, government agencies (e.g. EMEA, FDA, USDA, etc.) or in the scientific literature. No guarantee is given on its accuracy, integrity, sufficiency, actuality and opportunity, and any liability is denied. Read the site's DISCLAIMER.
In case of doubt contact the manufacturer or a veterinary professional.