Brand: STRIKEFORCE-S ®
Company: JUROX
FORMULATION: «spray-on/pour-on» for topical administration.
ACTIVE INGREDIENT(S): dicyclanil 50 g/L (= 5%)
CHEMICAL CLASS of the active ingredient(s): insect growth regulator (= IGR, cyanopyrimidine)
INDICATIONS: SHEEP
PARASITES CONTROLLED* (spectrum of activity)
* Country-specific differences may apply: read the product label.
- Prevention against blowfly strike on sheep, either off-shears or with any length of wool, against fly strike (Lucilia spp) for 18 to 24 weeks.
- Mulesing and marking wounds on sheep against fly strike (Lucilia spp) during the wound healing process.
RECOMMENDED DOSE*
* Can be slightly different in some countries: read the product label!
- Highest dose: approx. 0.6 - 2 ml (30 - 100 mg dicyclanil) per kg bodyweight.
Use recommendations (Australia):
Sheep weight (kg) | Dose rate (mL) | Vol.per treatment band (mL) | Number of bands |
For the prevention of body strike | |||
10 - 20 | 14 | 7 | 2 |
21 - 30 | 16 | 8 | 2 |
31 - 50 | 20 | 10 | 2 |
>50 | 24 | 12 | 2 |
For the prevention of body and crutch strike | |||
10 - 20 | 21 | 7 | 3 |
21 - 30 | 24 | 8 | 3 |
31 - 50 | 30 | 10 | 3 |
>50 | 36 | 12 | 3 |
For the prevention of fly strike after mulesing | |||
Up to 30 | 8 | 4 | 2 |
31 - 50 | 10 | 5 | 2 |
Read the product label for further details on dosing and administration.
SAFETY
- LD50 (acute oral) in rats: >5000 mg/kg (source: MSDS)
- LD50 (acute dermal) in rats: >5000 mg/kg (source: MSDS)
- Estimated hazard class according to the WHO classification of pesticides: not listed
Suspected poisoning? Read the article on dicyclanil safety in this site.
Withholding periods (=withdrawal times) for meat, milk & shearing (country-specific differences may apply: read the product label)
- Meat: Australia 14 days (ESI 60 to 120 days depending on wool length at treatment)
- Milk for human consumption: Not approved in Australia.
- Shearing: UK & Australia 3 months
You may be interested in the following articles in this site dealing with the general safety of veterinary products:
- Safety for humans
- Safety for domestic animals
- Safety for the environment
- Hazard classifications of pesticides
RESISTANCE PREVENTION
Risk of resistance? YES but rather low, mainly in Australia.
It has been shown that houseflies & blowflies resistant to cyromazine (another IGR vastly used for blowfly strike prevention) have some degree of cross-resistance to dicyclanil. However, resistance of blowflies to cyromazine is still quite unusual. It has been reported for Lucilia cuprina in a few locations in Australia, but so far not in the UK, other EU countries, South Africa or New Zealand. In those cases of cyromazine field resistance reported in Australia resistance factors were very low (about 2.3 for cyromazine, 1.3x for dicyclanil) and the concerned products were still providing protection according to registered label claims.
Alternative chemical classes/active ingredients to prevent resistance of blowflies to dicyclanil product rotation:
- Organophosphates (mainly diazinon). High blowfly resistance in Australia already.
- Synthetic pyrethroids (e.g. α-cypermethrin). Short protection periods.
- Macrocyclic lactones (mainly ivermectin).
- Spinosad. Short protection periods.
- Benzoylphenyl ureas (mainly diflubenzuron, triflumuron). No more approved for blowfly strike prevention in Australia due to resistance.
These alternative products may not be available in all countries, or may not be available as spray-ons/pour-ons.
Learn more about resistance and how it develops.
MARKETING
Are the active ingredients of this product ORIGINAL* or GENERICS**?
- GENERICS
*Meaning that they are still patent protected and generics are not yet available
**Meaning that they have lost patent protection and may be acquired from manufacturers of generic active ingredients other than the holder of the original patent.
COUNTRIES where this brand/product is marketed: Australia, New Zealand
GENERIC BRANDS available? YES, a few ones. This product itself is a generic version of ELANCO'S CLIK.
Click here to learn more about GENERIC vs. ORIGINAL drugs.
For an overview on the most used antiparasitic pour-on brands click here.
COMMENTS
SrikeForce-S Spray-on/Pour-on for sheep from JUROX is a ganeric version of CLIK (introduced by NOVARTIS AH in the late 1990s).
Dicyclanil is an insect development inhibitor introduced by NOVARTIS AH in the late 1990s. It has a very specific efficacy againts dipteran larvae. So far it is exclusively used in sheep, and not at all in other livestock, pets or agriculture.
For those visitors that have reached these depths of parasitipedia.net here's a personal message. I was very heavily involved in the discovery and development of dicyclanil and CLIK in the 1990s during my years in NOVARTIS AH. Click here if you want to know more about the discovery and development of these products.
DISCLAIMER
This article IS NOT A PRODUCT LABEL. It offers complementary information that may be useful to veterinary professionals and users that are not familiar with veterinary antiparasitics.
Information offered in this article has been extracted from publications issued by manufacturers, government agencies (e.g. EMEA, FDA, USDA, etc.) or in the scientific literature. No guarantee is given on its accuracy, integrity, sufficiency, actuality and opportunity, and any liability is denied. Read the site's DISCLAIMER.
In case of doubt contact the manufacturer or a veterinary professional.