Brand: COOPERS BLOWFLY & LICE JETTING FLUID
Company: COOPERS (MERCK AH - INTERVET)
FORMULATION: concentrate for dipping and jetting.
ACTIVE INGREDIENT(S): ivermectin 16 g/L (= 1.6%)
CHEMICAL CLASS of the active ingredient(s): macrocyclic lactone
INDICATIONS: SHEEP
PARASITES CONTROLLED* (spectrum of activity)
* Country-specific differences may apply: read the product label.
- Protects sheep against blowfly strike for up to 12 weeks. Protection against blowfly strike on sheep for up to 12 weeks under low to moderate fly pressure.
- Treats lice in long woolled sheep.
RECOMMENDED DOSE*
* Read the product label for further details on dosing and administration.
- Dilute 200ml of concentrate in 100L wate (equivalent to 32 mg/L = 32 ppm)
- Jetting for blowfly strike: Apply at least 2.5 L diluted jetting fluid by hand jetting or Modified Harrington Jetting race. Ensure thoroughly saturated wool to skin level.
- Hand Jetting for lice: When applied by hand jetting will treat biting lice until next shearing. Apply 0.5 L per month of wool growth ensuring fleece and skin are thoroughly wet to skin level.
- Hand dressing struck sheep: Saturate struck area thoroughly. Clipping the area prior to treatment is recommended.
SAFETY
- LD50 (acute oral) in rats: 50 mg/kg for the a.i. (source: MSDS)
- LD50 (acute dermal) in rats: >660 mg/kg for the a.i. (source: MSDS)
- Estimated hazard class of the formulation according to the WHO classification of pesticides: III slightly hazardous.
Withholding periods (=withdrawal times) for meat, milk & shearing (country-specific differences may apply: read the product label)
- Meat: Australia: 7 days (ESI = 7 days)
- Milk: Australia: Do not use in lactating sheep or within 28 days of lambing where milk or milk products may be used for human consumption
- Shearing: Australia: 6 weeks.
You may be interested in the following articles in this site dealing with the general safety of veterinary products:
- Safety for humans
- Safety for domestic animals
- Safety for the environment
- Hazard classifications of pesticides
RESISTANCE PREVENTION
Risk of resistance? YES.
There are no reports yet on resistance of body lice Bovicola (Damalinia) ovis to ivermectin. However, there are reports indicating cross-resistance with ivermectin in Lucilia cuprina diazinon and/or Diflubenzuron resistant strains, although the resistance factors were low (2-3x). A ten-fold resistance to ivermectin was also achieved after laboratory selection of a Lucilia cuprina field strain over 30 generations. This strongly indicates that Lucilia cuprina field populations may develop resistance to ivermectin if submitted to sustained selection pressure with ivermectin.
This means that if this product does not achieve the expected efficacy against the mentioned parasites, it may be due to resistance and not to incorrect use, which is usually the most frequent cause of product failure.
Alternative chemical classes/active ingredients for product rotation to prevent resistance of body lice to ivermectin:
- Neonicotinoids (e.g. imidacloprid). No efficacy against blowfly strike.
- Spinosad. Short protection periods.
Alternative chemical classes/active ingredients for product rotation to prevent resistance of Lucilia cuprina to ivermectin:
- Insect growth regulators: cyromazine, dicyclanil
- Spinosad. Short protection periods.
These alternative products may not be available in all countries, or may not be available for jetting.
Learn more about resistance and how it develops.
MARKETING
Are the active ingredients of this product ORIGINAL* or GENERICS**?
- GENERICS
*Meaning that they are still patent protected and generics are not yet available
**Meaning that they have lost patent protection and may be acquired from manufacturers of generic active ingredients other than the holder of the original patent.
COUNTRIES where this brand/product is marketed: Australia.
GENERIC BRANDS available? YES, a few ones in Australia.
Click here to learn more about GENERIC vs. ORIGINAL drugs.
For an overview on the most used antiparasitic concentrates for dipping/jetting click here.
COMMENTS
COOPERS BLOWFLY & LICE JETTING FLUID is a lousicide and blowfly strike preventative from COOPERS (MERCK AH - INTERVET) containing ivermectin.
Ivermectin is the parasiticide for livestock and pets most widely used worldwide, with hundreds if not thousands of generic brands. It was introduced in the early 1980s (by MS&D AgVet). Ivermectin is probably the best veterinary parasiticide ever developed, highly effective against roundworms as well as against numerous external parasites (ticks, flies, lice, mites, etc.), but not against tapeworms and flukes. Twelve weeks protection against blowfly strike is not outstanding compared with other products available against this parasite that may reach up to 24 weeks protection.
DISCLAIMER
This article IS NOT A PRODUCT LABEL. It offers complementary information that may be useful to veterinary professionals and users that are not familiar with veterinary antiparasitics.
Information offered in this article has been extracted from publications issued by manufacturers, government agencies (e.g. EMEA, FDA, USDA, etc.) or in the scientific literature. No guarantee is given on its accuracy, integrity, sufficiency, actuality and opportunity, and any liability is denied. Read the site's DISCLAIMER.
In case of doubt contact the manufacturer or a veterinary professional.