CHEMICAL CLASS of the active ingredient(s): piperazine derivative
INDICATIONS: CHICKEN, TUEKEY & SWINE
PARASITES CONTROLLED (spectrum of activity)
- Turkeys, chickens: Large roundworms (Ascaridia spp.)
- Swine: large roundworms (Ascaris suum) and nodular worms (Oesophagostomum spp.)
- Under 12 weeks of age: for each 1000 birds, use 10 fluid oz. (300 ml) of Wazine-34 in 20 U.S. gallons (76 liters) of drinking water.
- Over 12 weeks of age: for each 1000 birds, use 20 fluid oz. (600 ml) of Wazine-34 in 40 U.S. gallons (150 liters) of drinking water.
- Worm turkeys at 4-6 weeks of age and thereafter at 30 days or as needed.
- 4 to 6 weeks of age: for each 1000 birds, use 5 fluid oz. (150 ml) of Wazine-34 in 10 U.S. gallons (38 liters) of drinking water.
- Over 6 weeks of age: for each 1000 birds, use 10 fluid oz. (300 ml) of Wazine-34 in 20 U.S. gallons (76 liters) of drinking water.
- Treat replacement pullets at 8, 12, and 16 weeks of age. Treat broilers at 4 weeks of age or as needed.
- For each 100 lb. (45.5 kg) of herd weight: give 1/2 fluid ounce (15 ml) of Wazine-34 per U.S. gallon (3.8 liters) of drinking water.
- Treat sows and gilts before breeding and up to 2 weeks before farrowing, treat boars at any time, and treat pigs 1 week after weaning and every 30 days thereafter.
Read the product label for specific detail on dosage.
- LD50 (acute oral) in rats: >7900 mg/kg for piperazine
- LD50 (acute dermal) in rats: n.a.
Suspected poisoning? Read the article on piperazine safety in this site.
Withholding periods (=withdrawal times) in days for meat & milk (country-specific differences may apply: read the product label)
- Chicken & Turkey: 14 days.
- Swine: 21 days
- Eggs for human consumption: Do not use in chickens producing eggs for human consumption
WARNING !!!: Never use on humans, dogs or cats
You may be interested in the following articles in this site dealing with the general safety of veterinary products:
- Safety for humans
- Safety for domestic animals
- Safety for the environment
- Hazard classifications of pesticides
Risk of resistance development? Low
Are the active ingredients of this product ORIGINAL* or GENERICS**?
*Meaning that they are still patent protected and generics are not yet available
**Meaning that they have lost patent protection and may be acquired from manufacturers of generic active ingredients other than the holder of the original patent.
COUNTRIES where this brand/product is marketed: USA.
GENERIC BRANDS available? Yes, in most countries.
Click here to learn more about GENERIC vs. ORIGINAL drugs.
Click here for an overview on the most used antiparasitic feed additives and medicated feeds for livestock and horses.
WAZINE-34 is a classic dewormer for swine & poultry from FLEMING based on generic piperazine.
Piperazine was already used as a human medicine at the end of the 19th century. Its anthelmintic properties for animals were discovered in the 1950's. It is still used in livestock and pets, although it has been vastly replaced with more effective compounds, especially in ruminants (cattle, sheep and goats). It is also used in anthelmintics for humans, but also in antidepressants, antihistamines, antipsychotics, etc. Piperazine derivatives are also used in plastics, resins, and other industrial materials, as well as an adulterant in the psychedelic drug scene.
Piperazine is a narrow-spectrum anthelmintic, effective almost only against ascarid roundworms (e.g. Ascaris suum, Ascaridia spp, Parascaris equorum, Toxocara canis, etc). It is still moderately used in swine, poultry, horses, dogs and cats because ascarids are often the most damaging worms in these species. It is hardly used in ruminants.
Piperazine as well as pyrantel and the benzimidazoles (e.g. fenbendazole, febantel, albendazole, mebendazole, etc.) has no residual effect, i.e. it acts against the worms during a few hours after administration but is quickly metabolized and excreted. For this reason treatment must often be repeated for certain indications. This is in contrast with wormers containing macrocyclic lactones (e.g. milbemycin oxime, selamectin) that ensure efficacy against numerous roundworms during weeks after a single treatment.
This article IS NOT A PRODUCT LABEL. It offers complementary information that may be useful to veterinary professionals and users that are not familiar with veterinary antiparasitics.
Information offered in this article has been extracted from publications issued by manufacturers, government agencies (e.g. EMEA, FDA, USDA, etc.) or in the scientific literature. No guarantee is given on its accuracy, integrity, sufficiency, actuality and opportunity, and any liability is denied. Read the site's DISCLAIMER.
In case of doubt contact the manufacturer or a veterinary professional.