Brand: NOROMECTIN ® PREMIX 6 mg/g
Company: NORBROOK
FORMULATION: «feed additives and medicated feeds» for oral administration.
ACTIVE INGREDIENT(S): ivermectin: 6 mg/g (=0.6%)
CHEMICAL CLASS of the active ingredient(s): macrocyclic lactone
INDICATIONS: SWINE
PARASITES CONTROLLED* (spectrum of activity)
* Country-specific differences may apply: read the product label
Swine
- Gastrointestinal roundworms: Ascaris suum (adults and L4 larvae), Red stomach worm Hyostrongylus rubidus (adults and L4 larvae), Nodular worm Oesophagostomum spp. (adults and L4 larvae), Threadworm Strongyloides ransomi (adults and somatic larvae).
- Lungworms: Metastrongylus spp (adults).
- Lice: Haematopinus suis.
- Mange mites: Sarcoptes scabiei var. suis.
- The product given to pregnant sows before farrowing effectively controls transmission via the milk of S. ransomi to piglets.
RECOMMENDED DOSE*
*Can be slightly different in some countries: read the product label!
- In-feed use. For the production of medicated feedingstuff.
- The product can be incorporated into meal feed or pelleted feed.
- 0.1mg ivermectin per kg bodyweight per day (equivalent to 16.7mg Noromectin Premix for Swine per kg bodyweight per day) administered for 7 consecutive days.
- The dosage per tonne of feedingstuff (inclusion rate) should be adjusted to the current actual daily feed intake of the animals since this varies depending on age, general health, category of animals and animal husbandry (e.g. different environmental temperature, different feeding regime).
- To ensure thorough dispersion, 0.333kg or 1.67kg of the product (depending on weight of pigs) should be first mixed with 5kg feed ingredients before incorporation into the final mix.
- Read the product label for further details.
SAFETY
- LD50 (acute oral) in rats: ~4167 mg/kg (estimate according to WHO 2009 recommendation)
- Estimated hazard class according to the WHO: not applicable for veterinary medicines
Suspected poisoning? Read the article on ivermectin safety in this site.
Withholding period for meat (country-specific differences may apply: read the product label)
- Swine: UK 12 days
WARNING !!!: Never use on humans, dogs and cats
You may be interested in the following articles in this site dealing with the general safety of veterinary products:
- Safety for humans
- Safety for domestic animals
- Safety for the environment
- Hazard classifications of pesticides
RESISTANCE PREVENTION
Risk of resistance? NO
Resistance of gastrointestinal roundworms to ivermectin has not been reported yet in swine, in contrast with sheep, goats, cattle and horses, where it is very frequent worldwide.
This means that if this product does not achieve the expected efficacy against the mentioned parasites, it is likely to be due to incorrect use not to resistance
Alternative chemical classes/active ingredients to prevent resistance of gastroinitestinal roundworms through product rotation:
- Benzimidazoles, e.g. albendazole, febantel, fenbendazole, oxfendazole, etc. Similar or even worse resistance problems than macrocyclic lactones
- Imidazothiazoles, mainly levamisole. etc. Similar or even worse resistance problems than macrocyclic lactones
- Tetrahydropyrimidines, e.g. morantel, pyrantel (limited spectrum of activity)
These alternative products may not be available in all countries, or may not be available as injectables.
Although strictly speaking it is not yet needed, it may be advisable to rotate occasionally.
Learn more about resistance and how it develops.
MARKETING
Are the active ingredients of this product ORIGINAL* or GENERICS**?
- GENERICS
*Meaning that they are still patent protected and generics are not yet available
**Meaning that they have lost patent protection and may be acquired from manufacturers of generic active ingredients other than the holder of the original patent.
COUNTRIES where this product is marketed: UK and other EU countries
GENERIC BRANDS available? YES, numerous.
Click here to learn more about GENERIC vs. ORIGINAL drugs.
Click here for an overview on the most used antiparasitic feed additives and medicated feeds for livestock and horses.
COMMENTS
NOROMECTIN PREMIX from NORBROOK is one of the numberless generic brands with ivermectin.
The original brand, IVOMEC PREMIX, was introduced by MERIAL in the 1980s as a specific oral formulation of ivermectin for swine.
Ivermectin was the first macrocyclic lactone discovered and introduced in the 1980s by MS&D AgVet. It is the parasiticide for livestock and pets most widely used worldwide, with probably thousands of generic brands. Ivermectin is probably the best veterinary parasiticide ever developed, highly effective against roundworms as well as against numerous external parasites (ticks, flies, lice, mites, etc.). As all macrocyclic lactones, ivermectin used alone is ineffective against tapeworms and flukes, regardless of the delivery form.
There are also numerous mixtures of ivermectin with other active ingredients, as well as other formulations (injectables, pour-ons, drenches, feed additives).
DISCLAIMER
This article IS NOT A PRODUCT LABEL. It offers complementary information that may be useful to veterinary professionals and users that are not familiar with veterinary antiparasitics.
Information offered in this article has been extracted from publications issued by manufacturers, government agencies (e.g. EMEA, FDA, USDA, etc.) or in the scientific literature. No guarantee is given on its accuracy, integrity, sufficiency, actuality and opportunity, and any liability is denied. Read the site's DISCLAIMER.
In case of doubt contact the manufacturer or a veterinary professional