Brand: OVIMEC 0.8 mg/ml Oral Solution for Sheep.
PARASITES CONTROLLED (spectrum of activity)
- Gastrointestinal roundworms: Haemonchus contortus (adult, L4), Ostertagia circumcincta (adult, L4 and inhibited larval stages), Ostertagia trifurcata (adult), Trichostrongylus axei (adult), Trichostrongylus vitrinus (adult and L4), Trichostrongylus colubriformis (adult and L4), Cooperia curticei (adult and L4), Nematodirus battus (adult and L4), Nematodirus filicollis (adult), Strongyloides papillosus (adult), Oesophagostomum venulosum (adult), Trichuris ovis (adult), Chabertia ovina (adult).
- Lungworms: Dictyocaulus filaria. (adult and L4)
- Nasal bots, Oestrus ovis, all larval stages.
- 1 ml product/4 kg bw, equivalent to: abamectin 0.2 mg/kg bw
- LD50 (acute oral) in rats: abamectin a.i. 10 mg/kg (according to MSDS)
- LD50 (acute dermal) in rats: abamectin: a.i. >330 mg/kg (according to MSDS)
- Estimated hazard class according to the WHO: not applicable for veterinary medicines
Suspected poisoning? Read the articles on abamectin safety in this site.
Withholding periods (=withdrawal times) in days for meat & milk (country-specific differences may apply: read the product label)
- Meat: Ireland 16 days
- Milk: Ireland:
- Do not use in ewes producing milk for human consumption.
- Do not use in non-lactating ewes, including pregnant ewes, within 60 days of lambing.
WARNING !!!: Never use on humans, dogs or cats
You may be interested in the following articles in this site dealing with the general safety of veterinary products:
- Safety for humans
- Safety for domestic animals
- Safety for the environment
- Hazard classifications of pesticides
Risk of resistance of gastrointestinal roundworms to macrocyclic lactones (incl. abamectin): YES, resistance in ruminants is a very serious and increasing problem worldwide, particularly in sheep and goats. The most affected worm species are: Haemonchus spp, Ostertagia spp /Teladorsagia spp, Trichostrongylus spp, Nematodirus spp, Chabertia ovina.
Resistance of gastrointestinal roundworms to macrocyclic lactones (incl. abamectin) in sheep, goats and cattle has been reported almost worldwide, including the USA, UK, Australia and New Zealand. Based on the very abundant and frequent use of ivermectin and other macrocyclic lactones (with cross-resistance to ivermectin) in livestock it must be assumed that resistance of these roundworms to this chemical class will continue spreading and strengthening in the future.
- Benzimidazoles, e.g. albendazole, febantel, fenbendazole, oxfendazole, etc. Similar or even worse resistance problems than ivermectin
- Imidazothiazoles, mainly levamisole. etc. Similar or even worse resistance problems than ivermectin
- Monepantel: available only for sheep & goats in some countries (e.g. Australia, UK + EU, New Zealand). First cases of resistance reported in New Zealand in 2013.
- Nitroxinil (limited spectrum of activity)
- Tetrahydropyrimidines, e.g. morantel, pyrantel (limited spectrum of activity)
- Salicylanilides, e.g. closantel (limited spectrum of activity)
These alternative products may not be available in all countries, or may not be available as drenches.
This means that if this product does not achieve the expected efficacy against the mentioned parasites, it may be due to resistance and not to incorrect use, which is usually the most frequent cause of product failure.
Are the active ingredients of this product ORIGINAL* or GENERICS**?
*Meaning that they are still patent protected and generics are not yet available
**Meaning that they have lost patent protection and may be acquired from manufacturers of generic active ingredients other than the holder of the original patent.
COUNTRIES where this brand/product is marketed: Ireland
GENERIC BRANDS available? Yes a few ones. Abundant in Australia & New Zealand, rare elsewhere. This product itself contains generic abamectin.
Click here to learn more about GENERIC vs. ORIGINAL drugs.
For an overview on the most used antiparasitic drenches click here.
OVIMEC is an anthelmintic drench from OSMONDS containing generic abamectin.
Abamectin, a veteran endectocide introduced in the 1980s (by MSD AgVet → MERIAL), is considered as the "cheap" macrocyclic lactone. It is less potent and more toxic than ivermectin and other macrocyclic lactones but is often "good enough", with a similar spectrum of activity as ivermectin. Interestingly abamectin is widely used in livestock and horses in Australia and New Zealand but so far not in most of the EU, the USA and Canada. As for other macrocyclic lactones, abamectin has no efficacy whatsoever against tapeworms and flukes. It is also used in agricultural pesticides.
In ruminants, reducing the amount of feed slows down the exit flow of the rumen and prolongs the time during which the active ingredient remains there and is absorbed. Consequently it is advisable to reduce the access of animals to feed (especially to fresh pasture, not to water) 24 hours before administration. For the same reason, it is better to keep the animals away from food for about 6 hours after drenching. However sick or weak animals should not be kept away from food and fasting animals should have access to water.
Click here for general information on good practices for the prevention and control of gastrointestinal worms in livestock.
This article IS NOT A PRODUCT LABEL. It offers complementary information that may be useful to veterinary professionals and users that are not familiar with veterinary antiparasitics.
Information offered in this article has been extracted from publications issued by manufacturers, government agencies (e.g. EMEA, FDA, USDA, etc.) or in the scientific literature. No guarantee is given on its accuracy, integrity, sufficiency, actuality and opportunity, and any liability is denied. Read the site's DISCLAIMER.
In case of doubt contact the manufacturer or a veterinary professional.