Brand: ENDOGARD Palatable Allwormer

Company: VIRBAC


FORMULATION: «tablets» for oral administration; may be chewable, flavored, coated, etc, depending on the country

ACTIVE INGREDIENT(S):

  • OXIBENDAZOLE:
    • small dogs & puppies, cats & kittens: 112.5 mg/tablet
    • medium dogs up to 10 kg: 225 mg/tablet
    • large dogs up to 20 kg: 450 mg/tablet
  • PRAZIQUANTEL:
    • small dogs & puppies, cats & kittens: 25 mg/tablet
    • medium dogs up to 10 kg: 50 mg/tablet
    • large dogs up to 20 kg: 100 mg/tablet

CHEMICAL CLASS of the active ingredient(s):


INDICATIONS: DOGS & CATS

PARASITES CONTROLLED* (spectrum of activity):

Dogs

Cats


RECOMMENDED DOSE*:

  • For dogs & puppies, cats & kittens: 1 tablet every 5 kg bw (equivalent to 10 22.5 mg/kg oxibendazole; 5 mg/kg praziquantel)
  • For medium dogs up to 10 kg: 1 tablet every 10 kg bw (equivalent to 22.5 mg/kg oxibendazole; 5 mg/kg praziquantel)
  • For large dogs up to 20 kg: 1 tablet every 20 kg bw (equivalent to 22.5 mg/kg oxibendazole; 5 mg/kg praziquantel)
  • Read the roduct label for further details on dosing

* Can be slightly different in some countries: read the product label!


SAFETY

  • LD50 (acute oral) in rats: n.a. for the tablets. >10000 mg/kg for oxibendazole; 2840 mg/kg for praziquantel
  • Estimated Hazard Class according to the WHO: not applicable for veterinary medicines

Suspected poisoning? Read the article oxibendazole safety and/or praziquantel safety in this site.

Never use on cats tablets approved only for use on dogs, and vice-versa. Never use on small dogs tablets approved for large dogs. Learn more about tablets and their safety.

You may be interested in the following articles in this site dealing with the general safety of veterinary products:


RESISTANCE PREVENTION

Risk of resistance development? Very Low

Learn more about resistance and how it develops.


MARKETING

Are the active ingredients of this product ORIGINAL* or GENERICS**?

  • Oxibendazole: GENERIC (introduced in the 1970s)
  • Praziquantel: GENERIC (introduced in the 1970s)

*Meaning that they are still patent protected and generics are not yet available
**Meaning that they have lost patent protection and may be acquired from manufacturers of generic active ingredients other than the holder of the original patent.

COUNTRIES where this product is marketed: Neu Zealand
GENERIC BRANDS available? YES, in some countries, with more or less comparable composition

Click here to learn more about GENERIC vs. ORIGINAL drugs.


COMMENTS

ENDOGARD Palatable Allwormer for Dogs & Cats from VIRBAC is a classic allwormer tablet against roundworms and tapeworms wuth generic oxibendazole and praziquantel.

Oxibendazole is a veteran benzimidazole introduced in the 1970s (by SMITH KLINE → PFIZER→ ZOETIS) that is rather scarcely used in pets, horses or ruminants. It is a broad-spectrum anthelmintic effective against roundworms in the gut and the lungs, but not against those in the skin. It has no efficacy whatsoever against external parasites. It is scarcely to moderately used in pets and horses. Usage in livestock is marginal. It is not used in agriculture.

Praziquantel is another veteran isoquinoline anthelmintic introduced in the 1970s (by BAYER). It is still the most effective and most vastly used parasiticide against tapeworms, but without any efficacy against roundworms, fleas or ticks. Praziquantel adds efficacy against tapeworms (Dipylidium caninumTaenia spp, etc.) but has no efficacy whatsoever against roundworms, hookworms or whipworms. It is the anthelmintic most vastly used against tapeworms in pets and horses. There are hundreds of antiparasitic brands for pets & horses containing praziquantel. Usage in livestock is rather modest. It is not used in agriculture.

Oxibendazole and praziquantel have no residual effect, i.e. they act against the worms during a few hours after administration but are quickly metabolized and excreted. For this reason treatment must often be repeated for certain indications.

For an overview and a list of the most popular pet wormers click here.


DISCLAIMER

This article IS NOT A PRODUCT LABEL. It offers complementary information that may be useful to veterinary professionals and users that are not familiar with veterinary antiparasitics. 

Information offered in this article has been extracted from publications issued by manufacturers, government agencies (e.g. EMEA, FDA, USDA, etc.) or in the scientific literature. No guarantee is given on its accuracy, integrity, sufficiency, actuality and opportunity, and any liability is denied. Read the site's DISCLAIMER.

In case of doubt contact the manufacturer or a veterinary professional.

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