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Chlorpyrifos is an antiparasitic active ingredient used in veterinary medicine in dogs and livestock against external parasites. It is also used against agricultural and household pests. It belongs to the chemical class of the organophosphates.

As most organophosphates, chlorpyrifos products are used for topical administration, either as concentrates (for dipping or spraying) or in ready-to-use larvicidal dressings, pour-ons and a few ear-tags for livestock. Usage in dogs is irrelevant. Chlorpyrifos is sometimes used in combination with other compounds (mainly synthetic pyrethroids). Nowadays usage has strongly declined in most regions because it has been replaced by newer, more effective and less toxic compounds.

Chlorpyrifos was banned in the USA in 2018.

Resistance to all organophosphates is already very frequent worldwide, particularly in cattle ticks, houseflies, mosquitoes, fleas, etc.

The table below indicates some usual dosing recommendations for chlorpyrifos issued by manufacturers or documented in the scientific literature. They may not be approved in some countries.

Dosing recommendations for CHLORPYRIFOS
DOGS
Delivery Parasites Dose (against chlorpyrifos-susceptible parasites)
Dip, spray Ticks, mites, lice 420-700 ppm (=mg/L) in the wash, dep. on indication
CATTLE
Dip, spray Ticksflies, mites, lice 240-500 ppm (=mg/L) in the wash, dep. on indications; for replenishment follow the label instructions
Pour-on Ticksflies, mites, lice 3,5-14 mg/kg, dep. on weight and indications
SHEEP & GOATS
Dip, spray Mites, lice 375-450 ppm (=mg/L) in the wash, dep. on indications; for replenishment follow the label instructions
Pour-on Mites, lice 5-10 mg/kg, dep. on weight and indications
SWINE
Dip, spray Mites, lice 240-450 ppm (=mg/L) in the wash, dep. on indication
Pour-on Mites, lice 3,5-7 mg/kg, dep. on weight and indications
HORSES
Dip, spray Ticksflies, mites, lice 240-450 ppm (=mg/L) in the wash, dep. on indications; for replenishment follow the label instructions
SOUTH AMERICAN CAMELIDS
Dip, spray Ticks, mites, lice 400 (=mg/L) in the wash, dep. on indications; for replenishment follow the label instructions

DISCLAIMER: Liability is denied for any possible damage or harm to persons, animals or any other goods that could follow the transmission or use of the information, data or recommendations in this site by any site visitor or third parties.

Dosing recommendations for antiparasitics depend on national regulations. National regulatory authorities determine whether a product is approved for a given indication, i.e. use on a particular host at a specific dose and against a specific parasiteCheck the labels of the products available in your country for specific information on approved indications.


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