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Nitroxinil is an antiparasitic active ingredient used in veterinary medicine in livestock against internal parasites (some roundworms and liver flukes). It is not used against agricultural and household pests. It belongs to the chemical class of the halogenated phenols.

Nitroxinil is a narrow-spectrum anthelmintic effective against a few roundworms (mainly blood-sucking species), against flukes (e.g. Fasciola hepatica) and against certain myiasis. It is not effective against tapeworms or most external parasites. It is used moderately in ruminants as an injectable, often in combination with ivermectin. It is not used in swine, poultry, horses or pets.

In the EU nitroxinil is the only flukicide with an established MRL for bovine and ovine milk, i.e. it can be used on dairy animals respecting the withholding period established for each particular product.

The table below indicates some usual dosing recommendations for nitroxinil issued by manufacturers or documented in the scientific literature. They may not be approved in some countries.

Dosing recommendations for NITROXINIL
CATTLE
Delivery Parasites Dose (against nitroxinil-susceptible parasites)
Subcutaneous Gastrointestinal roundworms 7-12.5 mg/kg
Subcutaneous Fasciola hepatica 12.5-13 mg/kg
Subcutaneous Parafilaria bovicola 20 mg/kg
SHEEP & GOATS
Delivery Parasites  Dose (against nitroxinil-susceptible parasites)
Subcutaneous Gastrointestinal roundworms 7-12.5 mg/kg
Subcutaneous Oestrus ovis 20 mg/kg
Subcutaneous Fasciola hepatica 10-15 mg/kg
SWINE
Delivery Parasites  Dose (against nitroxinil-susceptible parasites)
Subcutaneous Fasciola hepatica 10-13 mg/kg

DISCLAIMER: Liability is denied for any possible damage or harm to persons, animals or any other goods that could follow the transmission or use of the information, data or recommendations in this site by any site visitor or third parties.

Dosing recommendations for antiparasitics depend on national regulations. National regulatory authorities determine whether a product is approved for a given indication, i.e. use on a particular host at a specific dose and against a specific parasite. Check the labels of the products available in your country for specific information on approved indications.


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