Brand: FLIMABEND ® 100 mg/g Suspension

Company: KRKA


DELIVERY FORM: «feed additives and medicated feeds» for use in drinking water.

ACTIVE INGREDIENT(S): flubendazole 100 mg/g (equivalent to 10%)

CHEMICAL CLASS of the active ingredient(s): benzimidazole


INDICATIONS: PIGS & CHICKENS


PARASITES CONTROLLED (spectrum of activity)*

Pigs

Chickens

* Country-specific differences may apply: read the product label.


RECOMMENDED DOSE*

Pigs:

  • Treatment of helminthiasis caused by Ascaris suum (adult stages and intestinal larval stages) in piglets, pigs for fattening and pregnant sows:
    • 1 mg flubendazole (= 10 mg product) per kg body weight daily via oral administration during 5 days, i.e. 1 g of the product per 100 kg body weight daily for 5 days.
  • Treatment of helminthiasis caused by Ascaris suum (adult stages) in piglets and pigs for fattening.
    • 2.5 mg flubendazole (= 25 mg product) per kg body weight daily via oral administration during 2 days, i.e. 2.5 g of the product per 100 kg body weight daily for 2 days.
  • Pigs should be grouped according to their bodyweight and dosed accordingly, in order to prevent under or overdosing.
Chickens:
  • 1.43 mg flubendazole (= 14.3 mg product) per kg body weight daily via oral administration during 7 days i.e. 1 g of the product per 70 kg body weight daily for 7 days.

Read the product label for additional use recommendations.

* Country-specific differences may apply: read the product label.


SAFETY

  • LD50 (acute oral) in rats: >5000 mg/kg (for the a.i.)
  • LD50 (acute dermal) in rats: n.a.

Suspected poisoning? Read the article on flubendazole safety in this site.

Withholding periods (=withdrawal times) in days for meat & eggs (country-specific differences may apply: read the product label)

  • Meat:
    • Chickens: UK, Ireland: 2 days
    • Pig: UK, Ireland
      • dose 1 mg/kg for 5 days: 3 days
      • dose 2.5 mg/kg for 2 days: 4 days
  • Eggs: Ireland zero days

WARNING !!!: Never use on humans, dogs or cats

You may be interested in the following articles in this site dealing with the general safety of veterinary products:


RESISTANCE PREVENTION

Risk of resistance? LOW

There are no reports on resistance of Ascaris suum to benzimidazoles in swine more than 40 years after their introduction for this use. The same applies to poultry worms.

This means that if this product does not achieve the expected efficacy against the mentioned parasites, it is likely that it is not due to resistance but to incorrect use, which is the most frequent cause of product failure.

However, there are a few reports on resistance of Oesophagostomum worms to benzimidazoleslevamisole and pyrantel in swine (mainly in Europe), but so far the problem is much less frequent than in sheep or cattle. To prevent or at least delay resistance development it is a good practice to periodically alternate anthelmintics (rotation) with different modes of action.

Alternative chemical classes/active ingredients to prevent resistance of gastrointestinal roundworms through product rotation in swine:

These alternative products may not be available in all countries or may not be effective against all the concerned parasites.

It is highly recommended to periodically check the resistance status of each property performing appropriate tests (e.g. fecal egg counts) under supervision of a veterinary doctor.

Learn more about resistance and how it develops.


MARKETING

Are the active ingredients of this product ORIGINAL* or GENERICS**?

  • GENERICS

*Meaning that they are still patent protected and generics are not yet available
**Meaning that they have lost patent protection and may be acquired from manufacturers of generic active ingredients other than the holder of the original patent.

COUNTRIES where this brand/product is marketed: UK, Ireland & EU countries
GENERIC BRANDS available? Yes, in some countries, but not too many. This product itself contains generic flubendazole

Click here to learn more about GENERIC vs. ORIGINAL drugs.

Click here for an overview on the most used antiparasitic feed additives and medicated feeds for livestock and horses.


COMMENTS

This product is a classic anthelmintic for pig& chickens from KRKA containing generic flubendazole.

Flubendazole is a veteran anthelmintic introduced in the 1970s (by JANSSEN). It has a broad-spectrum of activity against roundworms (gastrointestinal and pulmonary) but is ineffective against kidney worms (Stephanurus dentatus), tapeworms and flukesFlubendazole also kills eggs of roundworms (ovicidal activity). As all benzimidazoles, flubendazole has no efficacy whatsoever against external parasites (ticksflies, lice, mites, etc). Among the benzimidazoles flubendazole is quite comparable with mebendazole in terms of efficacy and safety. Flubendazole is moderately used in pig & poultry but rather scarcely in ruminants, horses or pets. It is not used in agriculture.

As all benzimidazoles (as well as other anthelmintics such as levamisole and tetrahydropyrimidines), flubendazole has no residual effect, i.e. it kills the parasites shortly after administration, but as soon as medicated feeding is interrupted it does not significantly protect the animals against re-infestation by infective stages in their environment.


DISCLAIMER

This article IS NOT A PRODUCT LABEL. It offers complementary information that may be useful to veterinary professionals and users that are not familiar with veterinary antiparasitics. 

Information offered in this article has been extracted from publications issued by manufacturers, government agencies (e.g. EMEA, FDA, USDA, etc.) or in the scientific literature. No guarantee is given on its accuracy, integrity, sufficiency, actuality and opportunity, and any liability is denied. Read the site's DISCLAIMER.

In case of doubt contact the manufacturer or a veterinary professional.

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