Brand: HORSE TO FOAL 2X
DELIVERY FORM: «medicated feed» for oral administration.
ACTIVE INGREDIENT(S): fenbendazole 10 g/kg (= equivalent to 1.0%)
CHEMICAL CLASS of the active ingredient(s): benzimidazole
PARASITES CONTROLLED (spectrum of activity)
- For the control of large strongyles (Strongylus edentatus, Strongylus equinus, Strongylus vulgaris, Triodontophorus spp.), small strongyles (Cyathostomum spp., Cylicocyclus spp., Cylicostephanus spp.), pinworms (Oxyuris equi), and ascarids (Parascaris equorum).
* Country-specific differences may apply: read the product label.
- 5 mg fenbendazole per kg body weight (2.27 mg fenbendazole per pound) in a ONE (1) DAY treatment for large strongyles, small strongyles and pinworms.
- Thoroughly mix the required amount of Horse to Foal 2X with feed ration.
- Example: a 1,000-lb horse should receive 0.50 pound (8 oz) of Horse to Foal 2X in a ONE (1) DAY treatment.
- 10 mg fenbendazole per kg body weight (4.54 mg fenbendazole per pound) in a ONE (1) DAY treatment for ascarids.
- Example: a 1.000-lb horse should receive 1.0 pound (16 oz) of Horse to Foal 2X in a ONE 11) DAY treatment.
- All horses must be eating normally to ensure that each animal consumes an adequate amount of medicated feed. Regular deworming at intervals of 6 to 8 weeks may be required due to the possibility of reinfection. Consult your veterinarian for assistance in the diagnosis, treatment and control of parasitism.
Read the product label for specific details on dosage.
- LD50 (acute oral) in rats: >10000 mg/kg ( for the a.i.)
- LD50 (acute dermal) in rats: n.a.
Suspected poisoning? Read the article on fenbendazole safety in this site.
Withholding periods (=withdrawal times) in days for meat & milk (country-specific differences may apply: read the product label)
- Meat: DO NOT USE IN HORSES INTENDED FOR HUMAN CONSUMPTION
WARNING !!!: Never use on humans, dogs or cats
You may be interested in the following articles in this site dealing with the general safety of veterinary products:
- Safety for humans
- Safety for domestic animals
- Safety for the environment
- Hazard classifications of pesticides
Risk of resistance? YES
- Small strongyles (cyathostomes). Resistance of small strongyles to benzimidazoles is widespread and frequent e.g. in the USA, UK and Europe, Argentina, Chile, Uruguay, etc.
- Parascaris equorum: Cases of tolerance to benzimidazoles have been also reported (e.g. in the USA).
This means that if this product does not achieve the expected efficacy against the mentioned parasites, it may be due to resistance and not to incorrect use, which is usually the most frequent cause of product failure.
Alternative chemical classes/active ingredients to prevent resistance of gastrointestinal roundworms through product rotation:
- Imidazothiazoles, mainly levamisole. Not approved for use in horses in many countries.
- Macrocyclic lactones: mainly ivermectin, moxidectin. But tolerance or resistance to these compounds have also been reported in Europe (e.g. in the UK, Germany, Italy), the USA, and Brazil.
- Tetrahydropyrimidines, mainly pyrantel (limited spectrum of activity), but resistance cases have also been reported (e.g. Australia, USA, Brazil, Japan).
- Piperazine. Effective only against certain gastrointestinal roundworms (mainly ascarids).
Learn more about resistance and how it develops.
Are the active ingredients of this product ORIGINAL* or GENERICS**?
*Meaning that they are still patent protected and generics are not yet available
**Meaning that they have lost patent protection and may be acquired from manufacturers of generic active ingredients other than the holder of the original patent.
COUNTRIES where this brand/product is marketed: USA.
GENERIC BRANDS available? Yes, in some countries, but not too many. This brand itself contains generic fenbendazole.
Click here to learn more about GENERIC vs. ORIGINAL drugs.
Click here for an overview on the most used antiparasitic feed additives and medicated feeds for livestock and horses.
HORSE TO FOAL 2X is a horse anthelmintic from DURVET containing generic fenbendazole.
Fenbendazole is a veteran anthelmintic introduced in the 1970s (by HOECHST, now MSD = MERCK ANIMAL HEALTH). Fenbendazole has a broad-spectrum of activity against roundworms (gastrointestinal and pulmonary) and, depending on the dose also against tapeworms, but is ineffective against flukes. Fenbendazole also kills eggs of roundworms (ovicidal activity). As all benzimidazoles, fenbendazole has no efficacy whatsoever against external parasites (ticks, flies, lice, mites, etc). Among the benzimidazoles fenbendazole is quite comparable with oxfendazole in terms of efficacy and safety. Fenbendazole is abundantly used worldwide in numberless generic brands for livestock, horses and pets.
As all benzimidazoles (as well as other anthelmintics such as levamisole, monepantel, and tetrahydropyrimidines), fenbendazole for oral administrartion has no residual effect, i.e. it kills the parasites shortly after administration, but as soon as medicated feeding is interrupted it does not significantly protect the animals against re-infestation by infective stages in their environment.
Both for livestock and pets fenbendazole is often used in combinations that broaden the spectrum of activity or try to overcome potential resistance. Typical mixtures for livestock include a flukicide (e.g. closantel, etc.) and/or a macrocyclic lactone, and/or levamisole, although such mixtures are not approved everywhere. For dogs and cats it is often combined with a taenicide (e.g. praziquantel).
This article IS NOT A PRODUCT LABEL. It offers complementary information that may be useful to veterinary professionals and users that are not familiar with veterinary antiparasitics.
Information offered in this article has been extracted from publications issued by manufacturers, government agencies (e.g. EMEA, FDA, USDA, etc.) or in the scientific literature. No guarantee is given on its accuracy, integrity, sufficiency, actuality and opportunity, and any liability is denied. Read the site's DISCLAIMER.
In case of doubt contact the manufacturer or a veterinary professional.